Skip to main content

Table 1 Population baseline characteristics and sub-analysis according to mean platelet volume

From: Mean platelet volume is associated with the presence of left atrial stasis in patients with non-valvular atrial fibrillation

 

Overall

MPV ≤ 9.4 fL

MPV > 9.4 fL

P

 

(n = 427)

(n = 245)

(n = 182)

 

Demographics

Age

68.2 ± 10.7

67.5 ± 11.5

69.0 ± 9.3

0.133

♀

32.1% (137)

31.4% (77)

33.0% (60)

0.736

Body Mass Index (Kg/m2)

28.7 ± 5.2

29.2 ± 4.4

28.1 ± 6.0

0.014

Clinical data

Congestive heart failure

49.4% (211)

45.7% (112)

54.4% (99)

0.076

Hypertension

83.4% (356)

83.3% (204)

83.5% (152)

0.945

Diabetes mellitus

24.6% (105)

24.1% (59)

25.3% (46)

0.777

Stroke or TIA

15.2% (65)

12.2% (30)

19.2% (35)

0.047

Vascular diseasea

49.6% (212)

46.5% (114)

53.8% (98)

0.135

AF episode duration >1 week

77.8% (332)

74.7% (183)

81.9% (149)

0.078

CHADS2 score

2.1 ± 1.2

2.0 ± 1.2

2.3 ± 1.3

0.034

CHA2DS2-VASc score

3.7 ± 1.7

3.5 ± 1.8

3.9 ± 1.7

0.081

Medication

Oral anticoagulants

34.4% (147)

33.9% (83)

35.2% (64)

0.782

Enoxaparin

31.1% (133)

32.2% (79)

29.7% (54)

0.570

Antiplatelet agents

48.9% (209)

48.6% (119)

49.5% (90)

0.857

ACE-i or ARB-II

69.6% (297)

65.7% (161)

74.7% (136)

0.045

Statin

41.2% (176)

39.6% (97)

43.4% (79)

0.428

Laboratory assessment

Haemoglobin (g/dL)

13.8 ± 1.9

13.9 ± 1.9

13.6 ± 1.8

0.089

Leukocytes (103/uL)

7.5 ± 3.1

7.4 ± 2.8

7.8 ± 3.6

0.247

Platelets (103/uL)

222.6 ± 86.2

240.6 ± 95.2

198.4 ± 65.1

<0.001

Plaquetocrit (%)

20.5 ± 7.2

20.8 ± 7.9

20.2 ± 6.2

0.774

MPV (fL)

9.3 ± 1.1

   

PDW (%)

16.2 ± 1.3

16.1 ± 1.4

16.3 ± 1.2

0.151

INR

1.4 ± 0.7

1.4 ± 0.7

1.4 ± 0.7

0.583

INR ≥ 2.0

17.1% (73)

16.3% (40)

18.1% (33)

0.624

aPTT time (s)

34.1 ± 7.7

33.0 ± 6.0

35.6 ± 9.5

0.078

Creatinine (umol/L)

111.7 ± 93.9

111.4 ± 107.8

112.1 ± 71.4

0.329

Estimated GFR – MDRD

71.1 ± 27.5

72.4 ± 26.8

69.3 ± 28.5

0.262

CRP (mg/L)

1.7 ± 3.5

1.5 ± 2.7

2.1 ± 4.3

0.213

Troponin I (ng/mL)

0.03 ± 0.07

0.03 ± 0.04

0.04 ± 0.10

0.032

Transthoracic echocardiogram data

iLAV (ml/m2)

60.4 ± 24.5

56.7 ± 21.9

64.7 ± 26.6

0.006

iLVdd (mm/m2)

29.6 ± 5.6

28.8 ± 5.5

30.5 ± 5.6

0.010

LVEF < 55%

24.8% (106)

24.5% (60)

25.3% (46)

0.853

  1. Legend: MPV Mean platelet volume, TIA Transient ischemic attack, AF Atrial fibrillation, ACE-i Angiotensin converting enzyme inhibitor, ARB-II Angiotensin II receptor blocker, PDW Platelet distribution width, INR International normalized ratio, CRP, C reactive protein, GFR Glomerular filtration rate, MDRD Modified diet in renal disease formula, LV Left ventricle, LAAT Left atrial appendage thrombi, DSEC Dense spontaneous echo contrast, LFV flow velocities Lowin the left atrial appendage, LA ABN Left atrial abnormality, aPTT Activated partial thromboplastin time, iLAV Indexed left atrial volume, iLVdd Indexed left ventricle diastolic diameter, LVEF Left ventricle ejection fraction.
  2. a vascular disease is defined as having at least one of the following: myocardial infarction, peripheral artery disease and complex aortic plaque.
Back to article page

BMC Cardiovascular Disorders

ISSN: 1471-2261

Contact us