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Figure 5 | BMC Cardiovascular Disorders

Figure 5

From: Integrative pathway dissection of molecular mechanisms of moxLDL-induced vascular smooth muscle phenotype transformation

Figure 5

Cytokine and growth factor theme analysis. IPA networks from 3h (A, B, D) and 21h (C) experiments, involving cytokines and growth factors as molecular hubs. Genes/proteins are illustrated as nodes and molecular relationships as connecting lines between two nodes (direct relationships as normal lines; indirect relationships as dashed lines). Molecular relationships are supported by at least one literature reference, or by canonical information stored in the IPKB. Grey nodes represent genes of interest, while white nodes represent hubs that were added by the IPA algorithm to connect a set of genes of interest.

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