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Table 1 Phenotypical characterisation of sex hormone-binding globulin in a Swedish population of men and women

From: Low sex hormone-binding globulin is associated with hypertension: a cross-sectional study in a Swedish population

 

Men 1,385

Women 1,397

  

Quartiles for SHBG

p-trend

 

Quartiles for SHBG

p-trend

 

All

Q1

Q2

Q3

Q4

 

All

Q1

Q2

Q3

Q4

 

SHBG

33±14

17.8

26.7

35.1

50.8

 

55±31

26.2

41.1

55.6

92.6

 

Age

47.8±11.8

42.2

45.6

48.8

54.4

<0.001

47.7±11.7

46.9

47.3

49.0

47.7

0.033

BMI

26.9±3.6

28.9

27.3

26.5

24.9

<0.001

26.8±5.3

30.1

27.2

26.5

24.9

<0.001

Fasting insulin

6.7±5.2

8.9

7.0

6.2

4.9

<0.001

6.2±4.4

8.5

6.2

5.1

4.7

<0.001

Fasting glucose

5.5±1.1

5.8

5.7

5.5

5.4

<0.001

5.3±1.1

5.7

5.4

5.1

5.1

<0.001

HOMA-IR

1.7±1.6

2.3

1.8

1.5

1.1

<0.001

1.5±1.3

2.2

1.5

1.2

1.1

<0.001

Hs-CRP

2.4±5.8

3.0

2.3

1.9

3.3

0.038

2.7±4.6

4.1

2.5

2.2

2.3

0.097

LDL

3.4±0.9

3.4

3.4

3.4

3.3

0.327

3.1±0.9

3.2

3.1

3.2

3.2

0.287

HDL

1.2±0.3

1.1

1.2

1.2

1.3

<0.001

1.4±0.3

1.2

1.4

1.5

1.5

<0.001

Triglycerides

1.5±0.9

1.9

1.5

1.3

1.1

<0.001

1.2±0.6

1.4

1.1

1.0

1.1

0.004

Systolic BP

123±16

126

124

123

123

<0.001

119±18

123

118

117

119

0.008

Diastolic BP

72±10

73.8

71.7

71.8

70.6

<0.001

69±10

70.0

68.4

67.8

68.2

0.007

Total Testosterone

14.3±4.4

11.2

13.4

15.2

17.5

<0.001

1.3±1.3

1.3

1.2

1.2

1.3

0.853

Oestradiol

127±56

125

128

124

132

0.026

320±396

255

328

337

363

<0.001

FAI

48.5±17.3

64.5

50.5

43.4

35.3

<0.001

3.1±5.8

5.7

2.9

2.4

1.4

<0.001

  1. SHBG= sex hormone-binding globulin, Q1 is the lowest quartile and Q4 is the highest. BMI=Body mass index, HOMA-IR= homeostatic model assessment insulin resistance, hs-CRP=high sensitive c-reactive protein, LDL=low density lipoprotein, HDL=high density protein, BP= blood pressure, FAI=free androgen index.
  2. General linear models to estimate mean values and differences between quartiles were used. The significance was estimated with p-value.