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Table 8 Sub-clinical atherosclerosis and adiposity

From: The relationship between DXA-based and anthropometric measures of visceral fat and morbidity in women

Carotid intima-media thickness

HR

SE

z

pvalue

95% CI

Model fit (Wald)

     

Lower

Upper

χ2

df

pvalue

A

          
 

VAT

1.50

0.09

6.6

2 × 10-11

1.33

1.69

43.8

1

4 × 10-11

 

DXA abdominal fat

1.29

0.07

4.5

4 × 10-6

1.16

1.45

20.0

1

8 × 10-6

 

BMI

1.39

0.08

5.5

2 × 10-8

1.23

1.55

30.5

1

3 × 10-8

 

Age

1.08

0.01

6.3

1 × 10-10

1.05

1.10

40.0

1

3 × 10-10

B

          
 

VAT

1.36

0.10

4.4

5 × 10-6

1.19

1.56

59.6

2

1 × 10-13

 

Age

1.06

0.01

5.0

3 × 10-7

1.04

1.09

   
  1. Cox proportional hazards regression (n = 801) showing unadjusted ORs (A) and best-fit model including visceral adipose fat (VAT) area and age (B). For evidence of the presented best-fit model and an analysis of residuals to account for co-linearity between adiposity variables, see Additional file 1: Tables S6 and S7, respectively. The study sample prevalence estimate (females > = 40 years) for sub-clinical atherosclerosis at follow-up was 0.27 (average time from baseline to follow up was 9.95 years, range 5–16 years). Explanatory variables VAT, DXA and BMI are all standardised, implying a change in hazard ratio per unit SD change. For Cox proportional hazards, the Wald model-fit statistic is presented to indicate the best model fit (StatCorp, Texas) that predicts onset of sub-clinical atherosclerosis (carotid intima-media thickness, cIMT). Abbreviation: CI - confidence interval.