Table 1 Demographics
Descriptives | BAV | TAV | p-value |
|---|---|---|---|
Age | 46.5 ± 11.6 | 46.3 ± 15.1 | 0.97 |
Males (n, %) | 6 (60%) | 10 (77%) | 0.40 |
Height (in) | 66.0 ± 4.2 | 70.0 ± 3.5 | 0.02* |
Weight (lbs) | 188.9 ± 52.9 | 180.3 ± 48.9 | 0.69 |
Body mass index | 30.1 ± 6.8 | 25.8 ± 5.8 | 0.10 |
Body surface area (m3) | 1.98 ± 0.32 | 1.99 ± 0.32 | 0.93 |
Systolic blood pressure (mmHg) | 118.3 ± 14.4 | 120.7 ± 13.4 | 0.69 |
Diastolic blood pressure (mmHg) | 71.7 ± 11.6 | 70.2 ± 7.9 | 0.72 |
Pulse pressure (mmHg) | 46.6 ± 11.4 | 50.6 ± 13.0 | 0.46 |
Mean arterial pressure (mmHg) | 87.2 ± 11.4 | 87.0 ± 7.9 | 0.97 |
Heart rate (bpm) | 64.1 ± 6.4 | 62.4 ± 12.6 | 0.70 |
Ejection fraction (%) | 59.0 ± 3.1 | 58.5 ± 3.2 | 0.67 |
Aortic root diameter (cm) | 3.14 ± 0.52 | 3.06 ± 0.34 | 0.75 |
Aortic root index (cm/m3) | 1.59 ± 0.18 | 1.56 ± 0.26 | 0.69 |
Ascending aortic diameter (cm) | 3.24 ± 0.46 | 2.87 ± 0.46 | 0.07 |
Ascending aortic index (cm/m3) | 1.67 ± 0.35 | 1.45 ± 0.20 | 0.40 |
Aortic stenosis: mild (n, %) | 5 (50%) | None | - |
Peak aortic velocity (cm/sec) | 217.5 ± 43.3 | 174.4 ± 45.8 | 0.001* |
Peak wall shear rate (sec-1) | 285.1 ± 18.9 | 180.1 ± 20.7 | 0.001* |
Aortic insufficiency: | 3 (30%) | 2 (15%) | 0.02* |
Trace (n, %) | 4 (40%) | 1 (7.7%) | |
Mild (n, %) | |||
Risk factors (n) | |||
Hypertension | 5 (50%) | 5 (38%) | 0.60 |
Hypercholesterolemia | 4 (40%) | 6 (46%) | 0.85 |
Coronary artery disease | 1 (10%) | 2 (15%) | 0.20 |
Tobacco use | 1 (10%) | 3 (23%) | 0.72 |
Diabetes mellitus | 1 (10%) | 1 (7.7%) | 0.44 |
Medications (n) | |||
ASA | 4 (40%) | 2 (15%) | 0.72 |
Anti-coagulants | 1 (10%) | 2 (15%) | 0.20 |
Beta-blockers | 5 (50%) | 3 (23%) | 0.72 |
ACE inhibitors/ARB | 3 (30%) | 3 (23%) | 0.42 |
Statins | 3 (30%) | 2 (15%) | 0.85 |