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Table 4 Adjustment for age in the association of AGT variants with coronary artery disease

From: Association of the angiotensinogen gene polymorphism with atherosclerosis and its risk traits in the Saudi population

Parameter Estimate S. E. t P-value Adjusted P-value 95% C. I.
       Lower Upper
A ≤44 * rs2148582A −0.694 0.341 −2.038 0.042* 0.168 −1.362 −0.026
A ≤63 * rs5051C −0.075 0.036 −2.05 0.04* 0.2 −0.146 −0.003
A ≤68 * rs5051C −0.119 0.04 −2.948 0.003*** 0.015 −0.197 −0.04
A ≤51 * rs3789679A −0.142 0.068 −2.068 0.039* 0.195 −0.276 −0.007
A ≤63 * rs3789679A −0.138 0.064 −2.167 0.03* 0.15 −0.263 −0.013
A ≤68 * rs4762A 0.081 0.038 2.16 0.031* 0.155 0.008 0.155
A ≤51 * rs2067853A −0.065 0.031 −2.106 0.035* 0.175 −0.126 −0.004
A ≤51 * rs7079G 0.066 0.025 2.687 0.007** 0.035 0.018 0.114
  1. The table shows the Bonferroni adjustments for the influence of age on the significance of the relationship between the SNPs and coronary artery disease. The data shows that the significance for association of the two variants rs5051C (for ages 63–68) and rs7079 (44–51) with coronary artery disease was retained following Bonferroni correction. *P < 0.05, **P < 0.01, ***P < 0.005., age; S.E. standard error, t, standard t test C.I., confidence interval.