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Table 3 The relationship of the angiotensinogen variants with coronary artery disease adjusted for the presence of its risk factors

From: Association of the angiotensinogen gene polymorphism with atherosclerosis and its risk traits in the Saudi population

Variable Estimate S. E t P-value 95%C.I
      Lower Upper
Sex −0.100 0.009 −11.296 <0.0001*** −0.122 −0.086
MI 0.555 0.010 58.143 <0.0001*** 0.574 0.613
HTN 0.036 0.010 3.509 <0.0001*** 0.009 0.051
T2DM 0.087 0.009 9.732 <0.0001*** 0.063 0.100
OBS −0.022 0.009 −2.435 0.015 −0.037 −0.003
Age 0.003 0.000 8.079 <0.0001*** 0.002 0.003
FH <0.00001 0.011 0.998 0.998 −0.021 0.021
rs7079T −0.020 0.009 −2.163 0.031 −0.035 0.001
MI _Intercept 1.255 0.395 3.174 0.002* 0.480 2.030
MI * rs3789679A −0.104 0.032 −3.229 0.001** −0.168 −0.041
MI * rs1926723C 0.092 0.035 2.597 0.009 0.022 0.161
MI * rs7079G 0.027 0.012 2.345 0.019 0.004 0.050
HTN _Intercept 0.371 0.549 0.675 0.500 −0.706 1.447
HTN* rs2148582A 0.065 0.021 3.095 0.002* 0.024 0.107
HTN * rs3789679A −0.074 0.035 −2.099 0.036 −0.143 −0.005
T2DM_ Intercept −0.089 0.418 −0.212 0.832 −0.908 0.731
T2DM * rs2148582A 0.056 0.024 2.347 0.019 0.009 0.103
T2DM * rs3789679A −0.099 0.044 −2.241 0.025 −0.186 −0.012
Gender_ Intercept −0.342 0.487 −0.702 0.482 −1.298 0.613
Female * rs2148582A 0.103 0.030 3.405 0.001** 0.044 0.162
Male * rs2148582G 1.256 0.645 1.948 0.051 −0.008 2.520
  1. The table displays the significant relationship of the angiotensinogen gene variants with coronary artery disease in presence of the various disease traits. Detailed analyses for the individual traits are given in the Additional file 1: Supplementary data file. S.E., standard error; t, Standard t-test MI, myocardial infarction; HTN, hypertension; T2DM, type 2 diabetes mellitus. OBS, obesity; FH, family history of coronary artery disease. *P < 0.01, **P < 0.0.001, ***P < 0.0001.