Transcatheter patent foramen ovale closure versus medical therapy for cryptogenic stroke: a meta-analysis of randomized clinical trials

Table 7 Meta-analysis of adverse events or complications

Complications –no./total no.	Closure trial		PC trial		Respect trial		Random effects model
Complications –no./total no.	Device	Medical	Device	Medical	Device	Medical	OR	95% CI	p-value
Major bleeding	10/378	4/374	7/204	12/210	8/499	9/481	1.02	0.46, 2.27	0.97
Atrial fibrillation	23/402	3/458	5/204	2/210	15/499	8/481	3.43	1.17, 10.00	0.02