Men | ||||
SUA tertiles | I ≤ 317μmol/L | II 318-380 μmol/L | III 381-976 μmol/L | P value for linear trend |
N | 896 | 902 | 898 | |
Age, years | 60 ± 10 | 59 ± 10 | 59 ± 11 | <0.001 |
Serum uric acid (SUA), μmol/L | 276 ±33 | 348 ± 18 | 449 ± 70 | - |
BMI, kg/m2 | 24.7 ± 2.9 | 25.8 ± 3.0 | 27.3 ± 3.4 | <0.001 |
SBP, mm Hg | 144 ± 20 | 144 ± 20 | 146 ± 20 | <0.001 |
DBP, mm Hg | 84 ± 12 | 85 ± 12 | 86 ± 12 | <0.001 |
Hypertension, n (%) | 482 (54%) | 546 (61%) | 571 (64%) | <0.001 |
Total cholesterol, mmol/l | 6.35 ± 1.19 | 6.40 ± 1.20 | 6.73 ± 1.20 | <0.001 |
HDL cholesterol, mmol/l | 1.51 ± 0.40 | 1.40 ± 0.39 | 1.26 ± 0.38 | <0.001 |
GFR ckd-epi, ml/min/1.73m2 | 96.7 (90.9, 102.4) | 95.5 (88.0, 102.5) | 93.4 (84.0, 101.5) | <0.001 |
ACR mg/mmol | 0.55 (0.38, 0.96) | 0.51 (0.33, 1.01) | 0.54 (0.34, 1.13) | 0.021 |
Use of antihypertensive drugs, n (%) | 74 (8%) | 87 (10%) | 155 (17%) | <0.001 |
Use of diuretics , n (%) | 2 (0.2%) | 5 (0.6%) | 13 (1.4%) | <0.001 |
Current smoker, n (%) | 351 (39%) | 300 (33%) | 294 (33%) | <0.001 |
Physically active, n (%) | 301 (33%) | 268 (30%) | 244 (27%) | <0.001 |
Women | ||||
SUA tertiles | I ≤ 244 μmol/L | II 245-297 μmol/L | III 298-681 μmol/L | P value for linear trend |
N | 1002 | 1001 | 1001 | |
Age, years | 58 ± 11 | 60 ± 10 | 62 ± 9 | <0.001 |
Serum uric acid (SUA), μmol/L | 206 ± 28 | 269 ± 15 | 354 ± 54 | - |
BMI, kg/m2 | 24.0 ± 3.5 | 25.6 ± 3.8 | 27.7 ± 4,6 | <0.001 |
SBP, mm Hg | 138 ± 23 | 143 ± 23 | 151 ± 25 | <0.001 |
DBP, mm Hg | 78 ± 13 | 81 ± 12 | 85 ± 14 | <0.001 |
Hypertension, n (%) | 446 (45%) | 534 (53%) | 679 (68%) | <0.001 |
Total cholesterol, mmol/l | 6.63 ± 1.39 | 6.82 ± 1.29 | 7.14 ± 1.32 | <0.001 |
HDL cholesterol, mmol/l | 1.76 ± 0.43 | 1.69 ± 0.43 | 1.54 ± 0.42 | <0.001 |
GFR ckd-epi, ml/min/1.73m2 | 96.9 (90.5,103.0) | 93.6 (86.0, 99.4) | 89.7 (79.4, 97.1) | <0.001 |
ACR, mg/mmol | 0.62 (0.41, 0.96) | 0.58 (0.41, 0.93) | 0.64 (0.42, 1.14) | <0.001 |
Use of diuretics, n (%) | 3 (0.3%) | 7 (0.7%) | 39 (3.9%) | <0.001 |
Use of antihypertensive drugs, n (%) | 65 (6.5%) | 107 (11%) | 148 (15%) | <0.001 |
Current smoker, n (%) | 339 (34%) | 315 (32%) | 278 (28%) | 0.001 |
Physically active, n (%) | 162 (16%) | 177 (18%) | 118 (12%) | <0.002 |