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Table 5 Cost, incremental cost and impact of screening strategies

From: Identification of effective screening strategies for cardiovascular disease prevention in a developing country: using cardiovascular risk-estimation and risk-reduction tools for policy recommendations

  Targeted screening Universal
  ≥ age 50† ≥ age 45 ≥ age 40 ≥ age 35 screening
Overall      
Estimated cost to detect 1 high risk individual, MYR (USD) 92.64 (29.73) 110.08 (35.33) 131.51 (42.20) 158.13 (50.75) 187.2 (60.08)
Incremental cost per additional high risk individual detected, MYR - 490.27 2060.12 15483.29 358444.85
(USD) - (157.34) (661.14) (4968.96) (115033.65)
NNS to prevent one CV event 62.24 76.14 96.64 123.95 146.73
NNS to prevent one CV event (sensitivity analyses) 168.47 206.07 261.57 335.48 397.15
Males      
Estimated cost to detect 1 high risk individual, MYR (USD) 69.05 (22.16) 82.64 (26.52) 99.44 (31.91) 121.01 (38.84) 144.13 (46.25)
Incremental cost per additional high risk individual detected, MYR - 306.21 1180.58 8825.99 258952.77
(USD) - (98.27) (378.88) (2832.47) (83104.23)
NNS to prevent one CV event 45.33 57.27 72.96 94.33 112.36
NNS to prevent one CV event (sensitivity analyses) 120.13 151.77 193.36 249.97 297.77
Females      
Estimated cost to detect 1 high risk individual, MYR (USD) 133.01 (42.69) 158.88 (50.99) 189.18 (60.71) 225.02 (72.21) 264.83 (84.99)
Incremental cost per additional high risk individual detected, MYR - 1426.50 8669.32 76295.96 293818.47
(USD) - (457.8) (2782.19) (24485.23) (94293.47)
NNS to prevent one CV event 85.72 105.59 129.78 165.01 194.20
NNS to prevent one CV event (sensitivity analyses) 240.97 394.25 364.83 463.95 545.95
  1. CV cardiovascular, NNS numbers needed to screen.
  2. MYR Malaysian Ringgit, USD US Dollar. 1.00 USD = 3.11600 MYR.
  3. * for incremental costs, reference screening strategy is directly to the left of screening strategy assessed.
  4. † first reference group (for ages ≥ 45).