Table 5 Cost, incremental cost and impact of screening strategies
Targeted screening | Universal | ||||
|---|---|---|---|---|---|
≥ age 50† | ≥ age 45 | ≥ age 40 | ≥ age 35 | screening | |
Overall | |||||
Estimated cost to detect 1 high risk individual, MYR (USD) | 92.64 (29.73) | 110.08 (35.33) | 131.51 (42.20) | 158.13 (50.75) | 187.2 (60.08) |
Incremental cost per additional high risk individual detected, MYR | - | 490.27 | 2060.12 | 15483.29 | 358444.85 |
(USD) | - | (157.34) | (661.14) | (4968.96) | (115033.65) |
NNS to prevent one CV event | 62.24 | 76.14 | 96.64 | 123.95 | 146.73 |
NNS to prevent one CV event (sensitivity analyses) | 168.47 | 206.07 | 261.57 | 335.48 | 397.15 |
Males | |||||
Estimated cost to detect 1 high risk individual, MYR (USD) | 69.05 (22.16) | 82.64 (26.52) | 99.44 (31.91) | 121.01 (38.84) | 144.13 (46.25) |
Incremental cost per additional high risk individual detected, MYR | - | 306.21 | 1180.58 | 8825.99 | 258952.77 |
(USD) | - | (98.27) | (378.88) | (2832.47) | (83104.23) |
NNS to prevent one CV event | 45.33 | 57.27 | 72.96 | 94.33 | 112.36 |
NNS to prevent one CV event (sensitivity analyses) | 120.13 | 151.77 | 193.36 | 249.97 | 297.77 |
Females | |||||
Estimated cost to detect 1 high risk individual, MYR (USD) | 133.01 (42.69) | 158.88 (50.99) | 189.18 (60.71) | 225.02 (72.21) | 264.83 (84.99) |
Incremental cost per additional high risk individual detected, MYR | - | 1426.50 | 8669.32 | 76295.96 | 293818.47 |
(USD) | - | (457.8) | (2782.19) | (24485.23) | (94293.47) |
NNS to prevent one CV event | 85.72 | 105.59 | 129.78 | 165.01 | 194.20 |
NNS to prevent one CV event (sensitivity analyses) | 240.97 | 394.25 | 364.83 | 463.95 | 545.95 |