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Table 1 Study population: age, serum lipids, biomarkers and cardiovascular risk factor distribution in cases and controls

From: Chromosome 1p13 genetic variants antagonize the risk of myocardial infarction associated with high ApoB serum levels

 

Cases (N = 1213)

Controls (N = 1561)

P

Age (years) M (IQTR)

60 (53-65)

61 (54-66)

0.03

Sex (M/F) (N)

852/361

1054/507

0.06

SBP (mmHg) M (IQTR)

130 (117-145)

140 (125-155)

<0.0001

DPB (mmHg) M (IQTR)

80 (72-86)

82 (77-90)

<0.0001

BMI (kg/m2) M (IQTR)

26 (23-28)

25.1 (23-27)

<0.0001

Lipid lowering therapy N(%)

59 (4.8)

55 (3.6)

0.55

Biochemistry M(IQTR)

   

T-Chol (mmol/L)

6.1 (5.4-6.9)

5.9 (5.2-6.6)

<0.0001

LDL-Chol (mmol/L)

4.2 (3.6-4.8)

3.9 (3.3-4.6)

<0.0001

HDL-Chol (mmol/L)

1 (0.9-1.3)

1.2 (1.0-1.5)

<0.0001

TG (mmol/L)

1.7 (1.2-2.4)

1.3 (0.9-1.8)

<0.0001

ApoA1 (g/L)

1.3 (1.2-1.5)

1.5 (1.3-1.7)

<0.0001

ApoB (g/L)

1.6 (1.4-1.9)

1.4 (1.2-1.7)

<0.0001

Risk Factors N(%)

   

Family History

400 (32)

358 (23)

<0.0001

Hypertension

561 (46)

817 (53)

0.001

Diabetes

151 (12)

72 (4.7)

<0.0001

Hypercholesterolemia

514 (42)

467 (30)

<0.0001

Hypertriglyceridemia

314 (25)

200 (13)

<0.0001

BMI > 30 kg/m2

227 (19)

197 (13)

<0.0001

Current Smokers

580 (48)

455 (29)

<0.0001

Physical Inactivity

523 (43)

536 (34)

0.001

  1. T-Chol = Total-Cholesterol; TG = Triglycerides.