Table 4 Hazard ratio (hr) estimates of adverse events among patients with and without diabetes treated with cypher or endeavour stents

Patient level analysis*

N = 342

N = 602

N = 1936

N = 3207

Death

0-823

31 (9.9)

36 (4.6)

2.03 (1.21-3.42)

0.0076

102 (5.6)

122 (3.2)

1.20 (0.90-1.60)

0.20

0-30

12 (43.9)

10 (20.5)

2.13 (0.88-5.15)

0.0942

43 (27.5)

40 (15.3)

1.52 (0.96-2.42)

0.077

31-365

15 (6.9)

18 (3.9)

1.69 (0.80-3.58)

0.1701

47 (3.7)

51 (2.1)

1.09 (0.71-1.68)

0.70

Cardiac death

0-823

17 (5.4)

12 (1.5)

3.54 (1.59-7.90)

0.0020

38 (2.1)

46 (1.2)

0.97 (0.60-1.58)

0.91

0-30

8 (29.3)

4 (8.2)

3.71 (1.03-13.4)

0.0449

22 (14.1)

25 (29.6)

1.09 (0.58-2.03)

0.79

31-365

8 (3.7)

7 (1.5)

3.38 (1.10-10.4)

0.0341

13 (1.0)

15 (0.6)

0.70 (0.29-1.72)

0.44

Noncardiac death

0-823

12 (3.8)

14 (1.8)

1.65 (0.72-3.79)

0.2347

41 (2.3)

52 (1,3)

1.19 (0.77-1.83)

0.44

0-30

4 (14.6)

6 (12.3)

1.22 (0.32-4.61)

0.7678

12 (7.7)

14 (5.4)

1.30 (0.56-3.02)

0.55

31-365

7 (3.2)

7 (1.5)

1.67 (0.51-5.44)

0.3984

24 (1.9)

27 (1.1)

1.18 (0.66-2.10)

0.57

Myocardial infarction

30-823

54 (19.6)

86 (12.7)

1.24 (0.86-1.79)

0.2522

319 (20.4)

543 (16.4)

0.98 (0.85-1.13)

0.79

0-30

41 (168)

68 (155)

1.24 (0.82-1.86)

0.3032

279 (206)

473 (210)

0.99 (0.85-1.16)

0.92

31-365

10 (5.2)

14 (3.5)

0.89 (0.33-2.40)

0.8195

35 (3.2)

49 (2.4)

0.93 (0.56-1.55)

0.79

Composite safety end point^†

30-823

31 (11.1)

48 (6.8)

1.45 (0.87-2.40)

0.1507

105 (6.5)

168 (4.7)

1.00 (0.76-1.31)

0.98

Target lesion revascularization

0-823

29 (9.8)

14 (1.8)

3.64 (1.10-12.1)

0.0350

81 (4.6)

76 (2.0)

2.14 (1.29-3.54)

0.003

In-stent restenosis

0-823

24 (8.0)

11 (1.4)

7.18 (1.59-32.4)

0.0103

60 (3.4)

56 (1.4)

1.97 (1.11-3.48)

0.020

Stent thrombosis

0-823

5 (1.6)

4 (0.5)

-

-

21 (1.2)

20 (0.5)

2.92 (0.95-8.93)

0.060

0-30

4 (14.7)

1 (2.0)

-

-

17 (10.9)

12 (4.6)

5.61 (1.14-27.6)

0.034

31-365

1 (0.5)

1 (0.2)

-

-

3 (0.2)

4 (0.2)

1.74 (0.23-13.2)

0.59

366-823

0 (0.0)

2 (0.8)

-

-

1 (0.3)

4 0.3)

-

-

Lesion level analysis

Target lesion revascularization

0-823

29 (7.3)

15 (1.4)

5.06 (2.65-9.69)

<.0001

86 (3.5)

80 (1.5)

2.08 (1.53-2.85)

<0.0001

In-stent restenosis

0-823

24 (6.0)

12 (1.1)

5.06 (2.48-10.3)

<.0001

63 (2.5)

60 (1.2)

2.08 (1.45-2.99)

<0.0001

Stent thrombosis

0-823

5 (1.2)

4 (0.4)

4.33 (1.02-18.4)

0.047

23 (0.9)

20 (0.4)

2.03 (1.10-3.76)

0.0234

0-30

4 (11.2)

1 (1.5)

11.6 (1.10-122)

0.0413

19 (9.0)

12 (3.5)

2.40 (1.15-4.99)

0.0194

31-365

1 (0.4)

1 (0.2)

1.84 (0.11-30.5)

0.6693

3 (0.2)

4 (0.1)

1.34 (0.29-6.08)

0.7074

366-823

0 (0.0)

2 (0.5)

-

-

1 (0.2)

4 (0.2)

1.68 (0.17-16.4)

0.66