Endpoint | Period (days) | Patients with ZES | Patients with SES | Adjusted HR* (95% CI) | P Value | ||
---|---|---|---|---|---|---|---|
No. of events | No./100 person-year | No. of events | No./100 person-year | ||||
Patient level analysis | N = 2,282 | N = 3,840 | |||||
Death | 0-823 | 135 | 6.3 | 159 | 3.3 | 1.35 (1.05-1.73) | 0.018 |
0-30 | 57 | 31.0 | 50 | 16.0 | 1.66 (1.10-2.50) | 0.016 | |
31-365 | 62 | 4.1 | 70 | 2.4 | 1.19 (0.82-1.73) | 0.388 | |
366-823 | 16 | 3.5 | 39 | 2.5 | 1.26 (0.67-2.34) | 0.475 | |
Cardiac death | 0-823 | 57 | 2.7 | 59 | 1.2 | 1.33 (0.89-2.00) | 0.183 |
0-30 | 32 | 17.4 | 29 | 9.3 | 1.39 (0.80-2.41) | 0.229 | |
31-365 | 21 | 1.4 | 23 | 0.8 | 1.17 (0.59-2.32) | 0.711 | |
366-823 | 4 | 0.9 | 7 | 0.4 | 1.36 (0.31-5.95) | 0.687 | |
Noncardiac death | 0-823 | 53 | 2.5 | 66 | 1.4 | 1.27 (0.87-1.87) | 0.217 |
0-30 | 16 | 8.7 | 20 | 6.4 | 1.32 (0.65-2.66) | 0.467 | |
31-365 | 31 | 2.1 | 34 | 2.1 | 1.25 (0.75-2.09) | 0.397 | |
366-823 | 6 | 1.3 | 12 | 0.8 | 1.39 (0.50-3.89) | 0.532 | |
Myocardial infarction | 31-823 | 66 | 3.5 | 108 | 2.5 | 0.98 (0.69-1.42) | 0.964 |
366-823 | 9 | 2.1 | 30 | 2.0 | 0.99 (0.43-2.28) | 0.992 | |
Target lesion revascularization | 0-823 | 110 | 5.3 | 91 | 1.9 | 2.16 (1.36-3.42) | 0.001 |
Stent thrombosis | 0-823 | 26 | 1.2 | 24 | 0.5 | 2.01 (0.76-5.34) | 0.159 |
0-30 | 21 | 11.5 | 13 | 4.2 | 3.62 (0.92-14.2) | 0.065 | |
31-365 | 4 | 0.3 | 5 | 0.2 | 1.17 (0.18-7.39) | 0.870 | |
366-823 | 1 | 0.2 | 6 | 0.4 | Not calculable | - | |
Lesion level analysis | N = 3,090 | N = 5,095 | |||||
Target lesion revascularization | 0-823 | 115 | 4.0 | 96 | 1.5 | 2.48 (1.87-3.27) | <0.0001 |
Stent thrombosis | 0-823 | 28 | 1.0 | 24 | 0.4 | 2.21 (1.26-3.87) | 0.006 |
0-30 | 23 | 9.3 | 13 | 3.1 | 2.75 (1.38-5.47) | 0.004 | |
31-365 | 4 | 0.2 | 5 | 0.1 | 1.47 (0.39-5.57) | 0.568 | |
366-823 | 1 | 0.2 | 6 | 0.3 | 1.22 (0.14-10.9) | 0.857 |