Effect of statin therapy on the progression of coronary atherosclerosis

Table 3 Stratified analyses by LDL-C levels at follow-up

Subgroup	Number of studies	Number of patients	I²index	PV change (95% CI)	P
≤70 mg/dL of LDL-C	4	429	0%	−5.9 mm³ (−9.6, –2.3)	<0.001
70–100 mg/dL of LDL-C	13	1,372	9%	−5.7 mm³ (−8.6, –2.7)	<0.001
≥100 mg/dL of LDL-C	5	370	0%	−4.2 mm³ (−9.9, 1.5)	0.15

Abbreviations: LDL-C, low-density lipoprotein-cholesterol; PV, plaque volume. I ² index: degree of heterogeneity in the meta-analysis.

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