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Table 2 Stratified analyses by dose and duration of follow-up of statin therapy

From: Effect of statin therapy on the progression of coronary atherosclerosis

Subgroup Number of studies Number of patients I 2index PV change (95% CI) P
1 3 99 0% −5.4 mm3 (−13.8, 3.0) 0.21
2 5 415 59% −7.8 mm3 (−20.2, 4.5) 0.21
3 2 41 0% −5.6 mm3 (−22.3, 11.2) 0.52
4 9 1,520 0% −5.2 mm3 (−7.3, –3.1) <0.001
  1. Abbreviations: PV, plaque volume. Subgroup 1: ≤10 mg/day of atorvastatin or an equivalent dose of other statins and ≤6 months of follow-up; subgroup 2: ≤10 mg/day of atorvastatin or an equivalent dose of other statins and >6 months of follow-up; subgroup 3: >10 mg/day of atorvastatin or an equivalent dose of other statins and ≤6 months of follow-up; subgroup 4: >10 mg/day of atorvastatin or an equivalent dose of other statins and >6 months of follow-up. I 2 index: degree of heterogeneity in the meta-analysis.