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Table 3 Effect of Doxorubicin, Vitamin E, and Telmisartan on rat serum CK-MB in IU/L

From: Vitamin E and telmisartan attenuates doxorubicin induced cardiac injury in rat through down regulation of inflammatory response

Groups

CK-MB level IU/L

Percent of changing

Before treatment

After treatment

 

Doxorubicin 15 mg./kg

685.8 ± 115.4

4759.1 ± 137.7 ††

594%

Doxo. + Vit E 100 mg./kg

587.6 ± 116.2

1008.7 ± 181.9 **

71.7%

Doxo. + Telmisartan 1 mg./kg

666.7 ± 146.1

1926.2 ± 155.4 ††**

189%

  1. The values are expressed as mean ± SEM.† P < 0.05, †† P < 0.01 (means of each group after treatment versus their means before treatment) by using paired t test.
  2. * P < 0.05, ** P < 0.01 (means of Vitamin E, and Telmisartan groups after treatment versus means of Doxorubicin group after treatment) by using LSD test.
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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