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Table 2 Effect of doxorubicin, Vitamin E, and Telmisartan on rat serum MDA in Ī¼mol/L

From: Vitamin E and telmisartan attenuates doxorubicin induced cardiac injury in rat through down regulation of inflammatory response

Groups

MDA level (Ī¼mol/L)

Precent of changing

Before treatment

After treatment

Ā 

Doxorubicin 15 mg./kg

3.27ā€‰Ā±ā€‰0.52

14.8ā€‰Ā±ā€‰0.45 ā€ ā€ 

352%

Doxo. + Vit E 100 mg./kg

2.98ā€‰Ā±ā€‰0.29

7.87ā€‰Ā±ā€‰0.99 ā€ ā€  **

164%

Doxo. + Telmisartan1mg/kg.

3.17ā€‰Ā±ā€‰0.29

11.1ā€‰Ā±ā€‰0.37 ā€ ā€  **

249.2%

  1. The values are expressed as meanā€‰Ā±ā€‰SEM. ā€  Pā€‰<ā€‰0.05, ā€ ā€  Pā€‰<ā€‰0.01 (means of each group after treatment versus their means before treatment) by using paired t test.
  2. * Pā€‰<ā€‰0.05, ** Pā€‰<ā€‰0.01 (means of Vitamin E, and Telmisartan groups after treatment versus means of Doxorubicin group after treatment) by using LSD test.