Common ALDH2 genetic variants predict development of hypertension in the SAPPHIRe prospective cohort: Gene-environmental interaction with alcohol consumption

Table 3 Association of ALDH2 genotypes with progression to hypertensions in SAPPHIRe cohort

	Incident cases/ 100 person-year (number of incident case)			Hazard ratio for Aa vs. AA (95%CI)	P	Hazard ratio for aa vs. AA (95%CI)	P
	AA	Aa	aa	Hazard ratio for Aa vs. AA (95%CI)	P	Hazard ratio for aa vs. AA (95%CI)	P
rs2238152	3.84(27)	3.12(11)	5.47(4)	0.93 (0.46-1.87)	0.83	2.88 (1.06-7.84)	0.03
rs671	4.08(25)	3.02(13)	5.00(4)	1.08 (0.51-2.29)	0.84	2.13 (0.77-5.89)	0.15
rs2158029	4.11(21)	2.69(13)	5.72(8)	0.83 (0.4-1.7)	0.60	1.94 (0.79-4.77)	0.15

ISSN: 1471-2261