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Table 1 Baseline characteristics of the enrolled patients with elevated NT pro-BNP levels

From: Association of cardiac and renal function with extreme N-terminal fragment Pro-B-type natriuretic peptide levels in elderly patients

  NT pro-BNP 3000-10000 pg/mL ( group A, n = 108) NT pro-BNP ≥10000 pg/mL (group B, n = 44) P
Age (years) 83.57 ± 3.33 83.84 ± 4.18 0.679
Male, n (%) 66 (61.1) 25 (56.8) 0.625
BMI (kg/m2) 22.64 ± 3.79 21.50 ± 3.33 0.084
SBP(mm Hg) 126.69 ± 20.21 128.39 ± 23.19 0.653
DBP (mm Hg) 68.25 ± 12.37 66.32 ± 16.54 0.487
Underlying commodities disease, n (%)    
Coronary artery disease 89(82.4) 37(84.1) 0.803
Atrial fibrillation 43(39.8) 15(84.1) 0.447
Diabetes mellitus 37(34.3) 19(43.2) 0.303
Hypertension 81(75.0) 36(81.8) 0.367
COPD 13(12.0) 4(99.1) 0.602
Respiratory failure 13(12.0) 7(15.9) 0.523
Cancer 29(26.9) 10(22.7) 0.860
Liver disease 10(9.3) 5(11.4) 0.694
MODS 6(5.6) 1(2.3) 0.383
Impaired renal function 39(36.1) 25(56.8) 0.019
Infection 57(52.8) 28(63.6) 0.223
Acute myocardial infarction 7(6.5) 4(9.1) 0.951
Death 9(8.3) 15(34.1) <0.001
Echocardiographic parameters    
LVEF (%) 54.88 ± 10.44 53.41 ± 9.98 0.427
Left atrial diameter (mm) 39.39 ± 6.43 38.07 ± 5.34 0.231
Right atrial diameter (mm) 37.81 ± 6.85 36.39 ± 5.22 0.216
Interventricular septum (mm) 10.69 ± 1.57 10.80 ± 1.75 0.729
Posterior wall (mm) 10.06 ± 1.28 10.14 ± 1.75 0.753
LV diastolic dimension (mm) 49.98 ± 6.51 50.55 ± 5.42 0.613
LV systolic dimension (mm) 35.67 ± 6.41 35.93 ± 5.74 0.265
Fractional shortening (%) 29.81 ± 5.72 29.20 ± 4.79 0.297
Laboratory data    
Creatinine (mg/dL) 1.24(0.92-1.82) 1.39(0.91-4.57) 0.001
CK-MB (ng/dL) 2.5(0.90-368) 3.63(1.72-5.77) 0.023
Serum albumin(g/dL) 33.44 ± 5.11 32.83 ± 6.76 0.540
C-reactive protein (mg/dL) 3.07(0.86-7.58) 3.44(1.025-8.6) 0.375
Medication, n (%)    
ACEIs or ARBs 7 (6.5) 20 (45.5) 0.803
β-blockers 16(36.4) 48(44.4) 0.362
  1. NT pro-BNP, N-terminal fragment pro-B-type natriuretic peptide;NS, not significant; BMI, body mass index; SBP, Systolic blood pressure; DBP, diastolic blood pressure ;HF, heart failure; LV, left ventricular; MODS, multiple organ dysfunction syndrome; CK-MB, MB isoenzyme of creatine kinase; COPD, chronic obstructive pulmonary disease. Data were shown as mean ± SD, percentages and median values (quartile 1, quartile 3) for different parameters.