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Table 1 Baseline characteristics of the enrolled patients with elevated NT pro-BNP levels

From: Association of cardiac and renal function with extreme N-terminal fragment Pro-B-type natriuretic peptide levels in elderly patients

 

NT pro-BNP 3000-10000 pg/mL ( group A, n = 108)

NT pro-BNP ≥10000 pg/mL (group B, n = 44)

P

Age (years)

83.57 ± 3.33

83.84 ± 4.18

0.679

Male, n (%)

66 (61.1)

25 (56.8)

0.625

BMI (kg/m2)

22.64 ± 3.79

21.50 ± 3.33

0.084

SBP(mm Hg)

126.69 ± 20.21

128.39 ± 23.19

0.653

DBP (mm Hg)

68.25 ± 12.37

66.32 ± 16.54

0.487

Underlying commodities disease, n (%)

   

Coronary artery disease

89(82.4)

37(84.1)

0.803

Atrial fibrillation

43(39.8)

15(84.1)

0.447

Diabetes mellitus

37(34.3)

19(43.2)

0.303

Hypertension

81(75.0)

36(81.8)

0.367

COPD

13(12.0)

4(99.1)

0.602

Respiratory failure

13(12.0)

7(15.9)

0.523

Cancer

29(26.9)

10(22.7)

0.860

Liver disease

10(9.3)

5(11.4)

0.694

MODS

6(5.6)

1(2.3)

0.383

Impaired renal function

39(36.1)

25(56.8)

0.019

Infection

57(52.8)

28(63.6)

0.223

Acute myocardial infarction

7(6.5)

4(9.1)

0.951

Death

9(8.3)

15(34.1)

<0.001

Echocardiographic parameters

   

LVEF (%)

54.88 ± 10.44

53.41 ± 9.98

0.427

Left atrial diameter (mm)

39.39 ± 6.43

38.07 ± 5.34

0.231

Right atrial diameter (mm)

37.81 ± 6.85

36.39 ± 5.22

0.216

Interventricular septum (mm)

10.69 ± 1.57

10.80 ± 1.75

0.729

Posterior wall (mm)

10.06 ± 1.28

10.14 ± 1.75

0.753

LV diastolic dimension (mm)

49.98 ± 6.51

50.55 ± 5.42

0.613

LV systolic dimension (mm)

35.67 ± 6.41

35.93 ± 5.74

0.265

Fractional shortening (%)

29.81 ± 5.72

29.20 ± 4.79

0.297

Laboratory data

   

Creatinine (mg/dL)

1.24(0.92-1.82)

1.39(0.91-4.57)

0.001

CK-MB (ng/dL)

2.5(0.90-368)

3.63(1.72-5.77)

0.023

Serum albumin(g/dL)

33.44 ± 5.11

32.83 ± 6.76

0.540

C-reactive protein (mg/dL)

3.07(0.86-7.58)

3.44(1.025-8.6)

0.375

Medication, n (%)

   

ACEIs or ARBs

7 (6.5)

20 (45.5)

0.803

β-blockers

16(36.4)

48(44.4)

0.362

  1. NT pro-BNP, N-terminal fragment pro-B-type natriuretic peptide;NS, not significant; BMI, body mass index; SBP, Systolic blood pressure; DBP, diastolic blood pressure ;HF, heart failure; LV, left ventricular; MODS, multiple organ dysfunction syndrome; CK-MB, MB isoenzyme of creatine kinase; COPD, chronic obstructive pulmonary disease. Data were shown as mean ± SD, percentages and median values (quartile 1, quartile 3) for different parameters.