Cases/Controls | Crude RR | Adjusted RR (95 % CI)* | |
---|---|---|---|
Ischemic stroke | 5519/55,022 | ||
No use of any therapy | 1513/15,499 | 1.00 | 1.00 (reference) |
Current use of warfarin monotherapy | 896/13,238 | 0.67 | 0.65 (0.59, 0.71) |
Below therapeutic range (INR: <2)† | 63/667 | 0.95 | 0.93 (0.71, 1.22) |
Within therapeutic range (INR: 2–3)† | 132/1838 | 0.71 | 0.69 (0.57, 0.83) |
Above therapeutic range (INR: >3)† | 31/361 | 0.86 | 0.82 (0.57, 1.20) |
Unknown therapeutic range† | 670/10,372 | 0.64 | 0.62 (0.56, 0.69) |
Current use of aspirin monotherapy | 2002/18,399 | 1.11 | 1.05 (0.98, 1.13) |
Intracranial hemorrhage | 689/6858 | ||
No use of any therapy | 114/1365 | 1.00 | 1.00 (reference) |
Current use of warfarin monotherapy | 242/2214 | 1.41 | 1.29 (1.00, 1.68) |
Below therapeutic range (INR: <2)† | 13/126 | 1.32 | 1.16 (0.62, 2.16) |
Within therapeutic range (INR: 2–3)† | 34/356 | 1.25 | 1.13 (0.74, 1.72) |
Above therapeutic range (INR: >3)† | 13/47 | 3.63 | 3.26 (1.67, 6.38) |
Unknown therapeutic range† | 182/1685 | 1.39 | 1.29 (0.98, 1.69) |
Current use of aspirin monotherapy | 172/2210 | 0.97 | 0.92 (0.70, 1.19) |