Skip to main content

Table 6 Difference in left ventricular rotational parameters between participants with dilated cardiomyopathy as compared to healthy controls

From: Heart Disease and Left Ventricular Rotation – A Systematic Review and Quantitative Summary

Study Details Matched Controls Apical Rot Basal Rot Twist Torsion Time to Peak Twist Peak Untwist Rate Untwist Rate Time to Peak Untwist Additional Notes
Buakhamsri et al. 2009 Case–control Level 3 D&B = 19 2D-STE*** No          DCM separated into sub-groups who had either a wide or narrow QRS complex. Narrow-QRS group had reduced untwisting velocity as compared to controls while wide-QRS complex had a further reduced untwisting velocity.
van Dalen et al. 2010 Case–control Level 3 D&B = 19 2D-STE*** Yes     
Liu et al. 2010 Case–control Level 3 D&B = 19 2D-VVI*** Yes      
Popescu et al. 2009 Case–control Level 3 D&B = 19 2D-STE** No        DCM were separated into sub-groups who had normal or reversed apical rotation. Torsion was lower in those with normal rotation compared to controls. Torsion was further reduced in those with opposite apical rotation (essentially torsion was lost). Basal rotation was not different between the two DCM groups. 31/50 participants had opposite rotation at either the base or the apex.
Meluzin et al. 2009 Case–control Level 3 D&B = 18 2D-STE*** Yes      18/37 participants had opposite rotation of either the apex or base.
Saito et al. 2009 Case–control Level 3 D&B = 18 2D-STE** Yes       
Kanzaki et al. 2006 Case–control Level 3 D&B = 17 MRI Tagging No     In those with DCM, the apex turned with the base at mid-systole and did not rotate counter clockwise throughout contraction as in healthy controls.
van Dalen et al. 2008 Case–control Level 3 D&B = 17 2D-STE*** Yes       
Sade et al. 2008 Case–control Level 3 D&B = 15 2D-STE** No     DCM separated into sub-groups who had either ischemic or non-ischemic disease. Both groups had similar LV rotation characteristics. 15/34 participants had opposite rotation at either the base or the apex.
  1. D & B; Downs and Black score, MRI; magnetic resonance imaging, 2D-STE; two dimensional speckle tracking echocardiography, 2D-VVI; two dimensional velocity vector imaging, ***indicates that mitral leaflets and luminal obliteration were used for identifying the basal and apical images respectively, **indicates that mitral leaflets and location inferior to papillary muscle were used for identifying the basal and apical images respectively, Apical Rot; apical rotation, Basal Rot; basal rotation, DCM; dilated cardiomyopathy, ; significant increase in heart disease group as compared to healthy controls, significant decrease in heart disease group as compared to healthy controls, ; no significant difference between heart disease group as compared to healthy controls.