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Table 4 Association of new AMI hospitalization and current use of NSAIDs by mean dose of NSAIDs used per day

From: Risk of new acute myocardial infarction hospitalization associated with use of oral and parenteral non-steroidal anti-inflammation drugs (NSAIDs): a case-crossover study of Taiwan's National Health Insurance claims database and review of current evidence

NSAIDs used (DDDs per day)

Crude OR

95% CI

Adjusted OR*

95% CI

Oral celecoxib

      

   low dose (> 0, < 0.5)

1.11

0.15 -

7.91

1.39

0.18 -

10.70

   high dose (≥ 0.5)

1.49

1.05 -

2.11

1.47

1.02 -

2.12

Oral ns-NSAIDs overall

      

   low dose (> 0, < 0.5)

1.22

0.85 -

1.76

1.12

0.76 -

1.65

   high dose (≥ 0.5)

1.65

1.42 -

1.93

1.56

1.32 -

1.83

Parenteral ns-NSAIDs overall

      

   low dose (> 0, < 0.5)

3.77

2.73 -

5.19

2.96

2.12 -

4.14

   high dose (≥ 0.5)

14.60

3.45 -

61.87

11.79

2.73 -

50.99

  1. 95%CI = 95% confidence interval; ns-NSAIDs = non-selective NSAIDs; DDD = defined daily dose
  2. * Conditional logistic regression adjusted for important potential time-varying confounding variables of all discordant use of antihypertensive agents, angiotensin converting enzyme inhibitors or aldosterone receptor blockers, calcium channel blockers, statins, insulin, sulfonylurea, thiazolidinedione, and aspirin between case and control period
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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