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Figure 1 | BMC Cardiovascular Disorders

Figure 1

From: Association between bilirubin and cardiovascular disease risk factors: using Mendelian randomization to assess causal inference

Figure 1

A diagram representing assumed relations in the causal system. In this figure, the relation between bilirubin and CVD risk factors is of interest, but is potentially confounded by measured or unmeasured factors. Genotype at the UGT1A1*28 locus affects CVD risk factors only through its relation with bilirubin and is not subject to confounding. The CVD risk factors listed in Table 1 were considered.

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