Dosing practice of low molecular weight heparins and its efficacy and safety in cardiovascular inpatients: a retrospective study in a Chinese teaching hospital

Table 4 Risk factors for major adverse vascular events (univariable analysis)

Characteristics	N (%)		OR (95% CI) *	PValue
	Without major adverse vascular events (n=302)	Major adverse vascular events (n=10)
Age, ≥75 y	60 (20)	5 (50)	4.03 (1.13-14.38)	0.036
Female	72 (24)	5 (50)	3.19 (0.90-11.35)	0.071
Weight, >60 kg	235 (78)	10 (100)	--	0.086
STEMI	49 (16)	4 (40)	3.44 (0.94-12.65)	0.071
Hypertension	186 (62)	8 (80)	2.50 (0.52-11.95)	0.201
Diabetes mellitus	69 (23)	0	--	0.079
Severe RI	4 (1.3)	3 (30)	31.93 (5.99-170.30)	0.001
Inappropriate dose	269 (89)	9 (90)	1.104 (0.14-8.99)	0.701
Excess dose	2 (0.7)	2 (20)	37.5 (4.68-300.75)	0.005
Underdose	267 (88)	7 (70)	0.306 (0.08-1.24)	0.109
Major underdose	217 (72)	6 (60)	0.588 (0.162-2.134)	0.310

Abbreviations: STEMI, ST-segment elevation myocardial infarction; RI, renal insufficient; OR, odds ratio; CI, confidence interval.
*Reference groups include age<75 years, male, weight ≤60 kg, no STEMI, no hypertension, no diabetes mellitus, no severe RI, recommended dose, no excess dose, no underdose, no major underdose.

ISSN: 1471-2261