Characteristic | Overall | Case group | Control group | P-value |
---|---|---|---|---|
 | 3,858,840 | 164,463 [%] | 3,694,377 [%] |  |
With chronic kidney disease | 66,476 | 13,445 [8.18] | 53,031 [1.44] | <.0001 |
Without chronic kidney disease | 3,792,364 | 151,018 | 3,641,346 | Â |
Age group, years | ||||
50-59 | 1,750,009 | 54,586 [33.19] | 1,695,423 | <.0001 |
60-69 | 1,097,797 | 50,413 [30.65] | 1,047,384 | |
70-79 | 734,932 | 45,041 [27.39] | 689,891 | |
≥80 | 276,102 | 14,423 [8.77] | 261,679 |  |
Sex | ||||
Male | 1,863,738 | 125,311 [76.19] | 1,738,427 [47.06] | <.0001 |
Female | 1,995,102 | 39,152 | 1,955,950 | Â |
Comorbidities | ||||
Hypertension | 419,678 | 45,693 [27.8] | 373,985[10.1] | <.0001 |
Hyperlipidemia | 60,744 | 9,521 [5.8] | 51,223 [1.4] | <.0001 |
Smoking-related diagnosis | 262,913 | 17,183 [10.4] | 245,730 [6.7] | <.0001 |
Alcoholism-related diagnosis | 28,305 | 2,891 [1.8] | 25,414 [0.7] | <.0001 |
Uremia | 21,526 | 2,228 [1.4] | 19,298 [0.5] | <.0001 |
Charlson’s comorbidities Index score†| ||||
0 | 3,099,342 | 106,542 | 2,992,800 | 0.0336 |
1 | 494,593 | 35,179 | 459,414 | |
2 | 178,885 | 14,215 | 164,670 | |
3 | 50,181 | 5,264 | 44,917 | |
4 | 16,497 | 1,858 | 14,639 | |
5 | 5,752 | 659 | 5,093 | |
6 | 2,360 | 261 | 2,099 | |
7 | 1,269 | 101 | 1,168 | |
8 | 6,321 | 204 | 6,117 | |
9 | 2,384 | 100 | 2,284 | |
10+ | 1,256 | 80 | 1,176 | Â |
Follow-up in years | ||||
0 | 63,220 | 2,682 | 60,538 | - |
1 | 65,186 | 4,115 | 61,071 | |
2 | 67,987 | 4,446 | 63,541 | |
3 | 67,136 | 4,484 | 62,652 | |
4 | 3,519,426 | 144,228 | 3,375,198 | |
5 | 75,885 | 4,508 | 71,377 | Â |