Table 1 Demographic characteristics, body composition, metabolic parameters and medications of 133 morbidly obese patients
Variable | Total (n = 133) | Male (n = 54) | Female (n = 79) | P-value |
|---|---|---|---|---|
Age (years) | 43 (11) | 45 (11) | 41 (10) | 0.107 |
Hypertension* (yes/no) | 90 (68%) | 44 (81%) | 46 (58%) | 0.005 |
Type 2 diabetes (yes/no) | 38 (29%) | 25 (46%) | 13 (17%) | <0.001 |
Ischemic heart disease (yes/no) | 7 (5.3%) | 6 (11.1%) | 1 (1.3%) | 0.018 |
Current smoker (yes/no) | 20 (15%) | 6 (11%) | 14 (18%) | 0.340 |
Weight (kg) | 132 (22) | 146 (23) | 121 (16) | <0.001 |
Various measures of body composition | ||||
Waist-to-hip ratio | 0.99 (0.10) | 1.17 (0.07) | 0.94 (0.07) | <0.001 |
Waist-to-height ratio | 75.3 (6.4) | 79.2 (6.2) | 74.4 (5.9) | <0.001 |
Waist circumference (cm) | 131 (14) | 142 (12) | 124 (10) | <0.001 |
BMI (kg/m2) | 44.5 (5.6) | 46.1 (6.3) | 43.5 (4.8) | 0.008 |
Fat mass (kg) | 63 (13) | 66 (16) | 61 (11) | 0.055 |
Fat free mass (kg) | 69 (13) | 81 (10) | 61 (7) | <0.001 |
Visceral fat area (cm2 ) | 242 (48) | 262 (55) | 228 (37) | <0.001 |
Metabolic variables | ||||
apoB/apoA-1 ratio | 0.7 (0.2) | 0.7 (0.2) | 0.7 (0.2) | 0.550 |
Fasting insulin (pmol/L) | 100 (85) | 125 (120) | 87 (49) | 0.048 |
HOMA-IR† | 4.6 (4.4) | 6.1 (6.3) | 3.5 (2.0) | 0.002 |
Fasting glucose (mmol/l) | 6.0 (2.2) | 6.5 (2.7) | 5.4 (1.1) | 0.002 |
B-HbA1c (%) | 6.2 (1.3) | 6.5 (1.6) | 5.7 (0.7) | 0.001 |
Pulse pressure (mmHg) | 62 (16) | 63 (15) | 61 (17) | 0.471 |
Medication | ||||
β-blocker (yes/no) | 13 (10%) | 8 (15%) | 5 (6%) | 0.134 |
Calsium-channel blocker (yes/no) | 17 (13%) | 10 (19%) | 7 (9%) | 0.125 |
Inhibitors of the RAA-system (yes/no) | 37 (28%) | 23 (43%) | 14 (18%) | 0.003 |
Statins (yes/no) | 18 (14%) | 13 (24%) | 5 (6%) | 0.008 |