Table 1 SNPs associated with CHD in genome-wide association studies
SNP | Chr. | Gene | Risk allele | ORs (95% CI) | Risk allele frequency | |
|---|---|---|---|---|---|---|
| Â | Â | Â | Â | Â | Reported | Observed |
rs10757278 | 9 | CDKN2A/2B | G | 1.28 (1.22, 1.35) | 0.45 | 0.52 |
rs599839 | 1 | SORT1 | A | 1.17 (1.11, 1.22) | 0.78 | 0.78 |
rs3008621 | 1 | MIA3 | G | 1.11 (1.04, 1.19) | 0.26 | NA |
rs501120 | 10 | Unknown | T | 1.30 (1.12, 1.51) | 0.84 | 0.87 |
rs9818870 | 3 | MRAS | T | 1.15 (1.11, 1.19) | 0.15 | 0.15 |
rs3184504 | 12 | SH2B3 | T | 1.13 (1.08, 1.18) | 0.39 | 0.49 |
rs9982601 | 21 | MRPS6 | T | 1.20 (1.14, 1.27) | 0.13 | 0.14 |
rs12526453 | 6 | PHACTR1 | C | 1.12 (1.08, 1.17) | 0.65 | 0.67 |
rs6725887 | 2 | WDR12 | C | 1.17 (1.11, 1.23) | 0.14 | 0.13 |
rs1122608 | 19 | LDLR | G | 1.15 (1.10, 1.21) | 0.75 | 0.77 |
rs11206510 | 1 | PCSK9 | T | 1.15 (1.10, 1.21) | 0.81 | 0.82 |
rs1746048 | 10 | CXCL12 | C | 1.16 (1.09, 1.24) | 0.84 | 0.87 |