Clinical characteristics | No PAD (N = 3, 943) | PAD (N = 1, 169) | P value |
---|---|---|---|
Weight (Kg) | 76.5 ± 14 | 77.1 ± 14.3 |  |
Waist circumference (cm) | 98 ± 12 | 97.9 ± 12.8 |  |
BMI (Kg/M2) | 27.8 ± 4.3 | 27.8 ± 4.5 |  |
SBP (mmHg) | 136.4 ± 14.6 | 141 ± 14.6 | < 0.0001 |
DBP (mmHg) | 81.6 ± 8.3 | 83 ± 8.2 | < 0.0001 |
Heart rate (beats/min) | 72.8 ± 8.7 | 74.2 ± 8.2 | < 0.0001 |
   Age (years, mean ± SD) | 63.9 ± 8.7 | 64.1 ± 9.2 |  |
Median | 63 | 64 | Â |
Interquartile range | 58-70 | 58-70 | Â |
   Age class (%) |  |  |  |
45-54 years | 11.4 | 12.8 | Â |
55-64 years | 44 | 41 | Â |
65-74 years | 32.3 | 32.1 | Â |
75-84 years | 11.2 | 12.2 | Â |
≥85 years | 1.1 | 1.9 | 0.039 |
   Sex |  |  |  |
Male | 50.4 | 51 | Â |
Female | 49.6 | 49 | Â |
Race (%) | Â | Â | Â |
Caucasian | 99.5 | 99.6 | Â |
Black | 0.1 | 0.1 | Â |
Oriental | 0 | 0 | Â |
Other | 0.4 | 0.3 | Â |
   Marital status (%) |  |  |  |
Single (unmarried) | 4.9 | 4.5 | Â |
Married or living together | 79.7 | 68 | < 0.0001 |
Widowed | 11.4 | 13.5 | Â |
Divorced or separated | 3.9 | 13.9 | < 0.0001 |
Other | 0.1 | 0.1 | Â |
   Anamnesis (%) |  |  |  |
Hypertension | 73.7 | 77.3 | 0.016 |
Dyslipidemia | 45.2 | 37.6 | < 0.0001 |
Cigarette smoking | 30.2 | 25.2 | 0.0008 |
High alcohol intake | 6.1 | 8.1 | 0.015 |
Family history of early CHD | 17.4 | 41.8 | < 0.0001 |
Sedentary lifestyle | 64.7 | 61.2 | Â |
   Serum lipids (mg/dl) |  |  |  |
Total cholesterol | 216.3 ± 39.2 | 216.9 ± 38.3 |  |
HDL-cholesterol | 53.7 ± 13.4 | 51.9 ± 12.9 | < 0.001 |
LDL-cholesterol | 134.4 ± 35.4 | 134.8 ± 35.4 |  |
Triglycerides | 138.6 ± 62.7 | 156.4 ± 70 | < 0.0001 |
   Medication (%) |  |  |  |
Antihypertensive | 54.5 | 60.05 | 0.003 |
Other CV drug | 7.23 | 5.82 | Â |
Any lipid modifiers | 18.18 | 14.29 | 0.002 |
Statin treatment | 11.6 | 6.5 | < 0.0001 |