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Table 1 Relative Daily Potency of the HMG-CoA Reductase Inhibitors [Statins] and Non-statin Lipid-lowering Drugs

From: A Retrospective Cohort Study of the Potency of lipid-lowering therapy and Race-gender Differences in LDL cholesterol control

Drug Daily dose range
in study population
Effect on LDL Cholesterol*
[% decrease]
Relative potency† of lowest and highest dose
Statins    
Atorvastatin 5-80 mg 32-50% 0.89, 1.39
Fluvastatin 20-80 mg 22-35% 0.61, 0.97
Lovastatin 10-120 mg 21-50% 0.58, 1.39
Pravastatin 5-320 mg 15-40% 0.42, 1.11
Rosuvastatin 2.2-60 mg 39-60% 1.08, 1.67
Simvastatin 5-160 mg 22-50% 0.61, 1.39
Non-Statins    
Cholestyramine 4-16 g 4-9% 0.10, 0.25
Colesevelam 625-3750 mg 5-10% 0.14, 0.28
Colestipol 1-10 g 5-10% 0.14, 0.28
Ezetimibe 5-30 mg 10-20% 0.28, 0.56
Fenofibrate 27-320 mg 5-10% 0.14, 0.28
Gemfibrazole 300-1200 mg 5-10% 0.14, 0.28
Niacin 250-3000 mg 4-9% 0.10, 0.25
Omega 3-12 mg 4-5% 0.10, 0.14
  1. * References 13-15
  2. † Atorvastatin 10 mg per day assigned a daily potency weight of 1.