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Table 7 The profile of serum biomarkers

From: HYPEST study: profile of hypertensive patients in Estonia

 

Male (n = 272)

Female (n = 484)

  

Serum

biomarker

Mean ± SD

(95% CI)

Mean ± SD

(95% CI)

Reference valuesa

P-value for gender comparisonb

Na+

(mmol/l)

140.4 ± 2.2

(140.1-140.7)

140.3 ± 4.5

(139.9-140.7)

136-145

0.29

K+

(mmol/L)

4.3 ± 0.4

(4.3-4.4)

4.7 ± 6.1

(4.2-5.3)

3.5-5.1

0.01

Urea

(mmol/L)

6.1 ± 2.0

(5.8-6.3)

5.7 ± 1.6

(5.5-5.8)

≤65 yrs < 8.3

> 65 yrs < 11.9

0.009

Creatinine (μmol/L)

88.5 ± 35.8

(84.2-92.7)

68.4 ± 29.2

(65.7-71.0)

M 62-106

F 44-80

< 0.0001

Uric Acid (μmol/L)

391.6 ± 84.0

(381.5-401.6)

317.8 ± 81.1

(310.6-325.1)

M 202-417

F 143-339

< 0.0001

Albumin

(g/L)

44.6 ± 3.4

(44.2-45.0)

43.7 ± 2.8

(43.4-43.9)

35.0-52.0

< 0.0001

Cholesterol

(g/l)

5.5 ± 1.1

(5.4-5.6)

5.6 ± 1.2

(5.6-5.9)

< 5.0

0.007

Triglycerides (mmol/L)

1.9 ± 1.9

(1.7-2.1)

1.7 ± 1.5

(1.6-1.9)

< 2.0

0.23

HDL-Choles-terol (g/l)

1.4 ± 0.4

(1.3-1.4)

1.6 ± 0.4

(1.5-1.6)

> 1.0

< 0.0001

LDL-Choles-terol (g/l)

3.7 ± 1.0

(3.6-3.8)

3.9 ± 1.0

(3.8-3.9)

< 3.0

0.08

C-reactive Protein (mg/L)

3.8 ± 7.8

(2.7-4.8)

3.3 ± 5.0

(2.8-3.8)

< 5.0

0.92

  1. a http://www.kliinikum.ee/yhendlabor/index.php?option=com_content&view=article&id=48&Itemid=37; b Mann-Whitney U test; M - male; F - female; SD - standard deviation; CI - Confidence Interval; yrs - years; significant P-values (< 0.01) have been indicated in bold.