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Table 3 Sensitivity and PPV of MI-HMDC for non-fatal population estimates based on AHA classification of myocardial infarction

From: Can we monitor heart attack in the troponin era: evidence from a population-based cohort study

Group

1998

2003

 

Sn, 95% CI

PPV, 95% CI

Sn/PPV a

Sn, 95% CI

PPV, 95% CI

Sn/PPV a

Positive MI b

          

Total non-fatal

82.9

80.3, 85.6

77.3

74.2, 80.4

1.07 (+7.4)

74.6

72.9, 76.2

83.5

79.4, 87.6

0.89 (-10.7)

All males

83.2

80.2, 86.3

76.6

72.9, 80.3

1.09 (+8.6)

76.5

74.6, 78.3

85.6

81.0, 90.2

0.89 (-10.6)

All females

82.2

77.0, 87.3

79.1

73.4, 84.8

1.04 (+3.9)

69.6

65.7, 73.4

77.9

69.1, 86.8

0.89 (-10.7)

All 35-69 years

83.8

80.3, 87.4

81.6

78.0, 85.2

1.03 (+2.7)

77.4

75.3, 79.6

85.0

80.1, 89.9

0.91 (-8.9)

All 70-79 years

81.2

77.2, 85.3

70.0

64.4, 75.6

1.16 (+16.0)

69.9

67.0, 72.8

80.6

73.0, 88.1

0.87 (-13.3)

Any MI b

          

Total non-fatal

80.8

78.5, 83.1

92.2

90.2, 94.2

0.88 (-12.4)

73.8

72.2, 75.2

93.7

90.9, 96.4

0.79 (-21.3)

All males

80.5

77.9, 83.2

92.1

89.7, 94.4

0.87 (-12.6)

76.2

74.6, 77.7

94.3

(91.3, 97.3

0.81 (-19.2)

All females

81.6

76.9, 86.2

92.5

88.9, 96.2

0.88 (-11.8)

67.7

64.2, 71.2

91.9

86.0, 97.7

0.74 (-26.3)

All 35-69 years

80.7

77.5, 83.9

94.2

92.0, 96.4

0.86 (-14.3)

76.9

75.0, 78.8

94.7

91.6, 97.8

0.81 (-18.8)

All 70-79 years

80.8

77.6, 84.1

88.7

84.8, 92.6

0.91 (-8.9)

68.9

66.4, 71.3

91.7

86.4, 96.9

0.75 (-24.9)

  1. 95% CI: 95% confidence interval; AHA: American Heart Association; HMDC: Hospital Morbidity Data Collection; MI: myocardial infarction; MI-HMDC: MI coded in the HMDC; Positive MI: AHA Definite or Probable MI; Any MI: AHA Definite/Probable/Possible MI; PPV: positive predictive value; Sn: sensitivity.
  2. a Ratio of sensitivity to PPV: number in parentheses represents the percentage by which the HMDC over-estimates (+) or under-estimates (-) the number of cases of MI in the population as defined by the 'AHA criteria'.
  3. b Luepker et al [12].