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Table 6 Non-parametric comparisons of cardiac parameters after 4 weeks of exposure to isoproterenol and treatment with P188 in BL10 and mdx mice.

From: Membrane Sealant Poloxamer P188 Protects Against Isoproterenol Induced Cardiomyopathy in Dystrophin Deficient Mice

Measurement

Group

N

Median

Range

Overall p-value

Significantly different groups

Heart rate (bpm)

BL10 - Untx

3

450

421 - 476

  
 

BL10 - Iso

7

615

532 - 656

  
 

MDX - Untx

6

438

400 - 489

0.0004

BL10-Iso vs. MDX-Untx (p = 0.0267)

 

MDX - Iso

9

585

541 - 667

 

MDX-Untx vs. MDX-Iso (p = 0.0149)

 

MDX - Iso + P188

5

632

615 - 667

  
  1. Bpm - beats per minute; iso - isoproterenol; untx - untreated