Skip to main content

Table 1 Baseline parametric comparisons of cardiac parameters in untreated 10 week old BL10 and mdx mice.

From: Membrane Sealant Poloxamer P188 Protects Against Isoproterenol Induced Cardiomyopathy in Dystrophin Deficient Mice

  

BL10

 

MDX

 

Measurement

N

Mean ± SD

N

Mean ± SD

P-value

Heart rate (bpm)

5

473 ± 35

22

458 ± 48

0.5370

SF%

10

30.91 ± 1.64

9

32.60 ± 3.08

0.1471

EF%

10

56.37 ± 3.65

9

58.38 ± 2.29

0.1739

LVID (d) (mm)

10

4.00 ± 0.16

9

4.05 ± 0.19

0.5776

LVPW (d) (mm)

10

0.54 ± 0.06

9

0.56 ± 0.03

0.4305

LV mass (mg)

10

77.92 ± 8.36

9

72.33 ± 4.67

0.0945

AoV vel (mm/s)

5

1079 ± 138

9

969 ± 121

0.1439

Systolic BP (mmHg)

5

89 ± 6

22

73 ± 6

<0.0001

  1. Bpm - beats per minute; SF% - shortening fraction percent; EF% - ejection fraction percent; LVID(d) - left ventricular internal diameter in diastole; LVPW(d) - left ventricular posterior wall thickness in diastole; LV - left ventricle; AoV vel - aortic valve velocity; BP - blood pressure; mmHg - millimeters of mercury; SD - standard deviation; mm - millimeters; mm/s - millimeters per second; mg - milligrams