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Table 5 Multivariable Adjusted Rate Ratios for Physical Activity in the CAREMA Cohort, 1987-2003

From: Smoking, alcohol consumption, physical activity, and family history and the risks of acute myocardial infarction and unstable angina pectoris: a prospective cohort study

 

Acute Myocardial Infarction

Unstable Angina Pectoris

 
 

Cases/person-years

Adjust. 1a

Adjust. 2b

Cases/person-years

Adjust. 1a

Adjust. 2b

 
  

RR

95% CI

RR

95% CI

 

RR

95% CI

RR

95% CI

P heterogeneity c

Occupationally d

           

Men

           

None to light activity

222/65,190

1

reference

1

reference

132/65,190

1

reference

1

reference

 

Moderate to heavy activity

80/22,849

1.27

0.97, 1.66

1.37

1.05, 1.80

41/22,849

1.15

0.79, 1.66

1.21

0.84, 1.76

0.49

Women

           

None to light activity

82/88,459

1

reference

1

reference

75/88,459

1

reference

1

reference

 

Moderate to heavy activity

6/16,078

0.48

0.21, 1.10

0.57

0.25, 1.32

7/16,078

0.67

0.31, 1.48

0.72

0.33, 1.59

0.89

Non-occupationally e

           

Men

           

None to light activity

115/30,536

1

reference

1

reference

72/30,536

1

reference

1

reference

 

Moderate to heavy activity

187/57,503

0.91

0.71, 1.15

1.03

0.81, 1.31

101/57,503

0.69

0.51, 0.95

0.74

0.54, 1.02

0.41

Women

           

None to light activity

32/45,070

1

reference

1

reference

28/45,070

1

reference

1

reference

 

Moderate to heavy activity

56/59,466

1.57

1.00, 2.46

1.81

1.15, 2.87

54/59,466

1.42

0.88, 2.27

1.55

0.96, 2.49

0.76

  1. Adjust, adjustment; CI, confidence interval; RR, rate ratio.
  2. Table summary: Occupational physical activity seemed to be a risk factor for both AMI and UAP in men, while in women it was associated with lower risks of both coronary endpoints. However, these associations were only statistically significant in men for the risk of AMI after adjustment for possible intermediates. Non-occupational physical activity seemed to be protective in men, while it was found to be a risk factor in women, although these associations were only statistically significant for the risk of AMI in women. Associations seemed to be stronger with the risk of AMI than of UAP, although not statistically significant (p heterogeneity > 0.05).
  3. a Rate ratios adjusted for age at baseline (years), baseline cohort (PPHVZ or MORGEN), smoking status (never, ex- or current smoker), smoking frequency (cigarettes/day), smoking duration (years), total alcohol consumption (glasses/day), level of education (primary school/junior vocational education, secondary vocational education or vocational college/university), and family history of premature MI (yes/no).
  4. b Additionally adjusted for intermediates: total and HDL cholesterol levels (mmol/L), diabetes mellitus (yes/no), systolic blood pressure (mmHg), and body mass index (kg/m2).
  5. c Heterogeneity test for the difference in the RRs between AMI and UAP. The p values were similar for the models with and without adjustments for intermediates.
  6. d Additionally adjusted for non-occupational physical activity.
  7. e Additionally adjusted for occupational physical activity.
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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