Skip to main content

Table 6 Addition of Risk Markers to the FRS: Effect on Risk Prediction in Black Women

From: The contribution of a 9p21.3 variant, a KIF6 variant, and C-reactive protein to predicting risk of myocardial infarction in a prospective study

Markers Added

to FRS Model

Number Reclassified (%)

Net Number Reclassified

Correctly (NRI, P value)

AUC (P value)*

9p21

110 (27.2)

12 (0.013, 0.89)

0.734 (0.40)

KIF6

11 (2.7)

-1 (-0.023, 0.35)

0.723 (0.94)

CRP

31 (7.7)

13 (0.016, 0.70)

0.726 (0.63)

CRP + 9p21

118 (29.1)

14 (0.039, 0.70)

0.735 (0.39)

CRP + KIF6

33 (8.1)

9 (0.025, 0.60)

0.725 (0.83)

9p21 + KIF6

113 (27.9)

15 (0.042, 0.66)

0.733 (0.46)

CRP + 9p21 + KIF6

119 (29.3)

15 (0.002,0.99)

0.734 (0.46)

  1. * P value for change in AUC from AUC of the FRS model (0.723)