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Table 1 Framingham Risk Score Characteristics at Baseline Among White Participants

From: The contribution of a 9p21.3 variant, a KIF6 variant, and C-reactive protein to predicting risk of myocardial infarction in a prospective study

 

Men n = 1495

 

Women n = 2156

 

Baseline Value

β (P value)*

 

Baseline Value

β (P value)*

Age, y, mean (SD)

73.3 (5.7)

0.043 (0.0002)

 

72.3 (5.4)

0.18 (0.45)

Current smoker

10%

-0.19 (0.44)

 

12%

0.49 (0.01)

LDL, mg/dL, mean (SD)

124 (33)

NA§

 

135 (37)

NA§

LDL category

     

   < 100

24.4%

-0.13 (0.45)

 

16.8%

-0.18 (0.38)

   100-129

35.0%

reference

 

30.7%

reference

   130-159

28.0%

0.10 (0.49)

 

29.4%

-0.04 (0.80)

   160-189

10.0%

0.22 (0.29)

 

16.2%

0.10 (0.57)

   > = 190

2.7%

-0.19 (0.65)

 

6.9%

-0.23 (0.41)

HDL, mg/dL, mean (SD)

48 (13)

NA§

 

59 (16)

NA§

HDL category

     

   < 35

11.4%

0.16 (0.47)

 

1.9%

-0.24 (0.65)

   35-44

34.1%

0.090 (0.60)

 

14.2%

0.15 (0.43)

   45-49

18.3%

reference

 

13.0%

0.20 (0.30)

   50-59

20.5%

-0.21 (0.29)

 

26.9%

reference

   > = 60

15.6%

-0.030 (0.89)

 

43.9%

-0.18 (0.27)

Blood pressure category†

     

   Optimal

23.3%

-0.31 (0.14)

 

23.8%

0.22 (0.34)

   Normal

18.5%

reference

 

18.0%

reference

   high normal

20.2%

0.30 (0.13)

 

19.2%

0.46 (0.05)

   HTN stage I

23.8%

0.39 (0.04)

 

26.2%

0.58 (0.007)

   HTN stage II-IV

14.1%

0.21 (0.33)

 

12.8%

0.95 ( 0.00005)

Diabetes‡

13.0%

0.57 (0.0006)

 

8%

0.66 (0.001)

  1. * Coefficients from Cox regression model of Framingham Risk Score (FRS) variables.
  2. † Optimal (systolic < 120 mm Hg and diastolic < 80 mm Hg), normal blood pressure (systolic 120 to 129 mm Hg or diastolic 80 to 84 mm Hg), high normal blood pressure (systolic 130 to 139 mm Hg or diastolic 85 to 89 mm Hg), hypertension stage I (systolic 140 to 159 mm Hg or diastolic 90 to 99 mm Hg), and hypertension stage II-IV (systolic 160 or diastolic 100 mm Hg). When systolic and diastolic pressures fell into different categories, the higher category was selected. Blood pressure categorization was made without regard to the use of antihypertensive medication.
  3. ‡ Fasting serum glucose ≥140 or taking insulin or oral hypoglycemic medications.
  4. § Continuous cholesterol measures are not included in the FRS model
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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