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Table 1 Framingham Risk Score Characteristics at Baseline Among White Participants

From: The contribution of a 9p21.3 variant, a KIF6 variant, and C-reactive protein to predicting risk of myocardial infarction in a prospective study

  Men n = 1495   Women n = 2156
  Baseline Value β (P value)*   Baseline Value β (P value)*
Age, y, mean (SD) 73.3 (5.7) 0.043 (0.0002)   72.3 (5.4) 0.18 (0.45)
Current smoker 10% -0.19 (0.44)   12% 0.49 (0.01)
LDL, mg/dL, mean (SD) 124 (33) NA§   135 (37) NA§
LDL category      
   < 100 24.4% -0.13 (0.45)   16.8% -0.18 (0.38)
   100-129 35.0% reference   30.7% reference
   130-159 28.0% 0.10 (0.49)   29.4% -0.04 (0.80)
   160-189 10.0% 0.22 (0.29)   16.2% 0.10 (0.57)
   > = 190 2.7% -0.19 (0.65)   6.9% -0.23 (0.41)
HDL, mg/dL, mean (SD) 48 (13) NA§   59 (16) NA§
HDL category      
   < 35 11.4% 0.16 (0.47)   1.9% -0.24 (0.65)
   35-44 34.1% 0.090 (0.60)   14.2% 0.15 (0.43)
   45-49 18.3% reference   13.0% 0.20 (0.30)
   50-59 20.5% -0.21 (0.29)   26.9% reference
   > = 60 15.6% -0.030 (0.89)   43.9% -0.18 (0.27)
Blood pressure category†      
   Optimal 23.3% -0.31 (0.14)   23.8% 0.22 (0.34)
   Normal 18.5% reference   18.0% reference
   high normal 20.2% 0.30 (0.13)   19.2% 0.46 (0.05)
   HTN stage I 23.8% 0.39 (0.04)   26.2% 0.58 (0.007)
   HTN stage II-IV 14.1% 0.21 (0.33)   12.8% 0.95 ( 0.00005)
Diabetes‡ 13.0% 0.57 (0.0006)   8% 0.66 (0.001)
  1. * Coefficients from Cox regression model of Framingham Risk Score (FRS) variables.
  2. † Optimal (systolic < 120 mm Hg and diastolic < 80 mm Hg), normal blood pressure (systolic 120 to 129 mm Hg or diastolic 80 to 84 mm Hg), high normal blood pressure (systolic 130 to 139 mm Hg or diastolic 85 to 89 mm Hg), hypertension stage I (systolic 140 to 159 mm Hg or diastolic 90 to 99 mm Hg), and hypertension stage II-IV (systolic 160 or diastolic 100 mm Hg). When systolic and diastolic pressures fell into different categories, the higher category was selected. Blood pressure categorization was made without regard to the use of antihypertensive medication.
  3. ‡ Fasting serum glucose ≥140 or taking insulin or oral hypoglycemic medications.
  4. § Continuous cholesterol measures are not included in the FRS model