65) women (odds ratio 3.4, p = 0.013). The INSIG2 SNP was not associated with BMI, nor with other clinical variables. Conclusion Age and gender may influence the association of the INSIG2 obesity SNP with PVD and cerebrovascular disease in patients with pre-existing CVD."/>
From: Association of an INSIG2 obesity allele with cardiovascular phenotypes is gender and age dependent
Population | allele | freq | count | allele | freq | count | Total |
---|---|---|---|---|---|---|---|
Caucasian | C | 0.331 | 515 | G | 0.669 | 1041 | 1556 |
AA | C | 0.243 | 66 | G | 0.757 | 206 | 272 |
Utah | C | 0.265 | 60 | G | 0.735 | 166 | 226 |
Kenya | C | 0.275 | 78 | G | 0.725 | 206 | 284 |
Nigeria | C | 0.230 | 52 | G | 0.770 | 174 | 226 |