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Table 1 Clinical observations in healthy rats.

From: Increased susceptibility to cardiovascular effects of dihydrocapcaicin in resuscitated rats. Cardiovascular effects of dihydrocapsaicin

Dose (mg/kg) 0 1.0 2.0 2.2 2.4 3.0
Step 1 2 3 4 5 6
Mortality -- -- -- -- -- --
Clinical Observations       
   Apparent restlessness -- -- All -- -- --
   Increased activity -- -- Rat 2 -- -- Rat 1
   Circling in cage -- -- Rat 2 -- -- Rat 1
   Stiff tail -- -- Rat 2 -- -- Rat 1
   Lateral recumbency -- -- Rat 2 -- -- Rat 1
   Shallow respiration -- -- -- -- -- Rat 1
   Muscle tremors, thorax -- -- -- -- -- Rat 1
   Vocalizing -- -- Rat 5 -- -- --
   Piloerection -- -- -- Rat 2 Rat 2 Rat 2
   Red pinnae -- -- -- All All All
  1. The table summarizes the clinical observations during the infusion of vehicle and incremental doses of DHC in conscious healthy rats. If no observations were made this was noted as "--", and if an observation was made in all 6 animals this was noted as "All".