Sex differences in the combined effect of chronic stress with impaired vascular endothelium functioning and the development of early atherosclerosis: The Cardiovascular Risk in Young Finns study

Table 3 Regression analysis of the interaction between vital exhaustion and flow-mediated dilatation/carotid artery compliance in relation to IMT

	R²*	R²change**	p	N
FMD responses
FMD x VE¹	0.129	0.000	0.984	1602
(all FMD responses)
#FMD x VE¹	0.175	0.000	0.678	985
(all FMD responses)
FMD x VE¹ (women)	0.109	0.000	0.796	949
#FMD x VE¹ (women)	0.129	0.001	0.335	555
FMD x VE¹ (men)	0.136	0.001	0.483	653
#FMD x VE¹ (men)	0.189	0.000	0.631	430
CAC responses
CAC x VE ¹	0.121	0.001	0.250	1715
(all CAC responses)
#CAC x VE ¹	0.167	0.001	0.358	1076
(all CAC responses)
CAC x VE¹ (women)	0.108	0.000	0.651	999
#CAC x VE¹ (women)	0.135	0.003	0.185	593
*CAC x VE* ¹ *(men)*	*0.124*	*0.005*	*0.046*	*716*
*#CAC x VE* ¹ *(men)*	*0.177*	*0.009*	*0.025*	*483*

Note. VE = vital exhaustion, FMD = flow-mediated dilatation (%), CAC = carotid artery compliance (%/10 mmHg).
¹ The main effects were included in each analysis, but they are not presented in the table.
*Calculated for the whole model.
**Refers to the interaction term.
#Additionally adjusted for cardiovascular risk factors: LDL-cholesterol, HDL-cholesterol, triglycerides, systolic and diastolic blood pressure.

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