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Table 2 Difference in systolic blood pressure (SBP), diastolic blood pressure (DBP) and mean arterial pressure (MAP) associated with genotype.

From: Are "functionally related polymorphisms" of renin-angiotensin-aldosterone system gene polymorphisms associated with hypertension?

 

SBP

DBP

MAP

 

AGT polymorphism

MM

Reference group

MT

-0.0 (-4.2; 4.2)

-0.6 (-3.1; 1.9)

-0.4 (-3.3; 2.5)

TT

2.4 (-1.9; 6.7)

0.8 (-1.8; 3.4)

1.3 (-1.7; 4.3)

 

ACE polymorphism

II

Reference group

ID

-0.9 (-3.8; 1.8)

0.6 (-1.1; 2.2)

0.1 (-1.9; 1.9)

DD

0.2 (-3.1; 3.5)

0.5 (-1.5; 2.4)

0.4 (-1.9; 2.7)

 

AGTR1polymorphism

CC

Reference group

CA

5.7 (-3.9; 15.4)

2.4 (-3.4; 8.1)

3.5 (-3.2; 10.2)

AA

8.2 (-1.3; 17.7)

4.2 (-1.5; 9.8)

5.5 (-1.1; 12.1)

 

Combined AGT/ACE polymorphism

M/I

Reference group

T/D

0.1 (-3.1; 3.4)

0.6 (-1.3; 2.5)

0.4 (-1.8; 2.7)

 

Combined AGT/AGTR1polymorphism

M/C

Reference group

T/A

2.3 (-0.1; 4.6)

1.3 (-0.1; 2.8)

1.6 (-0.0; 3.3)

 

Combined ACE/AGTR1polymorphism

I/C

Reference group

D/A

2.1 (-0.1; 4.3)

1.4 (0.1; 2.7)

1.6 (0.1; 3.2)

 

Combined AGT/ACE/AGTR1polymorphism

M/I/C

Reference group

T/D/A

2.7 (-0.1; 5.4)

1.7 (0.1; 3.3)

2.0 (0.1; 3.9)

  1. Data are shown as differences relative to the respective reference group expressed in mm Hg (95% confidence intervals) adjusted for age, gender, body mass index, ethnicity and concomitant antihypertensive medication. Note that confidence intervals excluding 1 are statistically equivalent to a p < 0.05.