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Table 1 Prevalence of alleles and FRPs.

From: Are "functionally related polymorphisms" of renin-angiotensin-aldosterone system gene polymorphisms associated with hypertension?

Genotype

Number of alleles/FRPs

% prevalence of allele/FRP

Number of subjects with allele/FRP and HT

% prevalence of HT in group with allele/FRP

AGT

M

954

36.5

287

30.1

T

1662

63.5

561

33.9 (0.0512)

ACE

D

1352

51.3

451

33.5

I

1284

48.7

411

32.1 (0.4630)

AGTR1

C

402

15.4

109

27.1

A

2208

84.6

739

33.6 (0.0126)

AGT/ACE combination

M/I

385

12.9

107

30.1

T/D

764

27.7

270

35.3 (0.0560)

AGT/AGTR1 combination

M/C

294

10.7

83

28.2

T/A

1590

57.7

548

34.5 (0.0372)

ACE/AGTR1 combination

I/C

298

10.8

79

26.5

D/A

1253

45.4

420

33.5 (0.0227)

AGT/ACE/AGTR1 combination

M/I/C

203

7.4

56

27.6

T/D/A

803

29.1

279

34.7 (0.0555)

  1. Data are absolute numbers of alleles (2 alleles per person and 2 FRPs per person) and their relative prevalence in %. P-values from Fisher's exact test vs. the reference genotype (M, I and C alleles, respectively) for the % prevalence of HT are given in parentheses. Note that two alleles/FRPs were identified per subject.