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Table 4 Range of net costs and QALYs resulting from scenarios and one-way sensitivity analyses

From: Cost-utility of enoxaparin compared with unfractionated heparin in unstable coronary artery disease

 

QALY or cost per person

Item varied

Lower

Upper

Base case (per person):

not applicable

not applicable

   QALY gain 0.013

  

   Net cost -£317 (ie cost saving for enoxaparin)

  

Event free time gained

0.004 QALYs

0.014 QALYs

Quality of life associated with event

0.012 QALYs

na

Treatment duration

-£298

-£320

Length of stay

  

   Difference in length of stay

£42 (ie £3,305/QALY)

-£158

   Cost per length of stay

-£236

na

Revascularisations

  

   Difference in coronary artery bypass grafting rates

-£140

-£495

   Difference in angioplasty rates

-£242

-£368

   Cost of coronary artery bypass grafting

-£309

-£323

   Cost of angioplasty

-£311

-£360

Unfractionated heparin costs

  

   Unfractionated heparin loading dose and saline flush

-£314

-£318

   Unfractionated heparin drawn-up in saline

-£313

-£318

   Pump-related

-£312

-£318

   Monitoring (activate partial thromboplastin time tests)

-£308

-£318

   Nursing time

-£314

-£318

   Enoxaparin costs

-£314

-£326

Scenario 3: Treatment of cardiac events

  

(not mean length of stay)

  

   Myocardial infarction rate and recurrence of angina

-£174

-£184

   Cost to treat acute myocardial infarction

-£181

-£187

   Cost to treat angina

-£181

-£189

  1. Notes: See Table 2 for ranges used. As there was little difference between scenarios 1 and 2, we amalgamated the results. Negative net costs indicate cost saving if using enoxaparin. Net costs and QALY gains are not shown where unaffected by parameter changes. na means not avaliable.