From: Cost-utility of enoxaparin compared with unfractionated heparin in unstable coronary artery disease
Base case | Lower, Upper | |
---|---|---|
Effectiveness data | ||
Mean event free years. Values used in sets, not individually for each outcome. | ||
Life years gained | 0.010 | 0.002, same as base case |
Myocardial infarction free time gained | 0.007 | 0.008, 0.013 |
Time free from recurrent angina | 0.018 | 0.014, 0.022 |
Quality of life data | ||
Values used in sets, not individually for each outcome. Quality of | ||
life change associated with | ||
Death | 0.977 | same as base case, no upper |
myocardial infarction (Q-wave) | 0.160 | 0.102, no upper |
Non-Q-wave myocardial infarction | 0.088 | 0.056, no upper |
Resource use (per person) | ||
Treatment duration (days) | 2.6 | 2,8 |
Coronary artery bypass grafting rates at one year | 0.014 | -0.013,0.041 |
Angioplasty rates at one year | 0.042 | 0.014, 0.070 |
Length of stay at 30 days (days) | 0.40 | -0.50, 0 |
Myocardial infarction rates at one year (Model 3 only) | 0.006 | same as base case, 0.013 |
Recurrence of angina at one year (Model 3 only) | 0.017 | same as base case, 0.021 |
Drug treatment costs per person 1 | ||
Enoxaparin, drug alone per day | £12.16 | £9.00, £14.29 |
Unfractionated heparin loading dose & saline flush | £0.52 | £0.41, £0.73 |
Consumables for loading dose | £0.14 | same as base case, £0.16 |
Unfractionated heparin drawn-up in saline per day | £1.83 | £1.37, £2.46 |
Pump-related costs per day | £1.79 | £1.27, £2.54 |
Monitoring (aPTT tests) per day | £3.67 | 0, £3.81 |
Difference in nursing time between enoxaparin and | £3.39 | £2.95, £4.36 |
unfractionated heparin (cost over 2.6 days) | ||
Treatment costs (per person) | ||
( * including length of stay) | ||
Coronary artery bypass grafting* | £6,534 | £5,933, £6,952 |
Angioplasty* | £1,803 | £1,647, £2,823 |
Treatment of acute myocardial infarction* (Model 3 only) | £1,150 | £863, £1,385 |
Treatment of angina* (Model 3 only) | £549 | £418, £758 |
Per in-patient day | £399 | £196, same as base case |