Non-coronary artery cardiac disease

Section edited by Michel Noutsias

This section concerns all aspects of non-coronary artery cardiac disease including but not limited to: arrhythmias, congenital cardiac disease and cardiomyopathies. The section considers articles concerning the prevention, diagnosis and management, as well as related molecular genetics, and pathophysiology.

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  1. Research article

    Expression levels of atherosclerosis-associated miR-143 and miR-145 in the plasma of patients with hyperhomocysteinaemia

    An elevated level of homocysteine (Hcy) in the blood is designated hyperhomocysteinaemia (Hhcy) and is regarded as a strong risk factor for the development of atherosclerosis (ATH), although the association re...

    Kejian Liu, Saiyare Xuekelati, Yue Zhang, Yin Yin, Yue Li, Rui Chai, Xinwei Li, Yi Peng, Jiangdong Wu and Xiaomei Guo

    BMC Cardiovascular Disorders 2017 17:163

    Published on: 20 June 2017

  2. Research article

    Cardiac tissue oxidative stress and inflammation after vitamin D administrations in high fat- diet induced obese rats

    Obesity is associated with numerous metabolic and inflammatory disorders. The current study was aimed to evaluate the effects of vitamin D administration on the markers of oxidative stress and inflammation in ...

    Mahdieh Abbasalizad Farhangi, Ghazaleh Nameni, Ghazaleh Hajiluian and Mehran Mesgari-Abbasi

    BMC Cardiovascular Disorders 2017 17:161

    Published on: 19 June 2017

  3. Research article

    DNA methylation dysregulations in rheumatic heart valve disease

    The epigenetic changes underlying the development of rheumatic heart valve disease (RHVD) remain incompletely understood. Limited evidence suggests that abnormal DNA methylation might be involved in the pathog...

    Kangjun Shen, Hui Liu, Ran Jing, Jiangfeng Yi and Xinmin Zhou

    BMC Cardiovascular Disorders 2017 17:159

    Published on: 17 June 2017

  4. Research article

    Pulmonary hemodynamics and effects of phosphodiesterase type 5 inhibition in heart failure: a meta-analysis of randomized trials

    Previous studies suggested that phosphodiesterase 5 inhibitors (PDE5i) have a beneficial effect in patients with heart failure (HF), although the results were inconsistent. We performed a meta-analysis to eval...

    In-Chang Hwang, Yong-Jin Kim, Jun-Bean Park, Yeonyee E. Yoon, Seung-Pyo Lee, Hyung-Kwan Kim, Goo-Yeong Cho and Dae-Won Sohn

    BMC Cardiovascular Disorders 2017 17:150

    Published on: 12 June 2017

  5. Study protocol

    Design and rationale for the WARFA trial: a randomized controlled cross-over trial testing the therapeutic equivalence of branded and generic warfarin in atrial fibrillation patients in Brazil

    Warfarin is a commonly used anticoagulant. Whether a given dose of the different formulations of Brazilian warfarin will result in the same effect on the international normalized ratio (INR) is uncertain. The ...

    Carolina Gomes Freitas, Michael Walsh and Álvaro Nagib Atallah

    BMC Cardiovascular Disorders 2017 17:148

    Published on: 7 June 2017

  6. Research article

    Decreased cardiac mortality with nicorandil in patients with ischemic heart failure

    Effective treatments in heart failure (HF) patients with ischemic etiology have not been fully established. Nicorandil, combination of nitrate component and sarcolemmal adenosine triphosphate-sensitive potassi...

    Akiomi Yoshihisa, Yu Sato, Shunsuke Watanabe, Tetsuro Yokokawa, Takamasa Sato, Satoshi Suzuki, Masayoshi Oikawa, Atsushi Kobayashi and Yasuchika Takeishi

    BMC Cardiovascular Disorders 2017 17:141

    Published on: 31 May 2017

  7. Research article

    Approach selection of radiofrequency catheter ablation for ventricular arrhythmias originating from the left ventricular summit: potential relevance of Pseudo Delta wave, Intrinsicoid deflection time, maximal deflection index

    Ventricular arrhythmias (VAs) originating from the left ventricular summit is a challenge for radiofrequency catheter ablation (RFCA). The present study aimed to investigate the appropriate RFCA strategy for V...

    Cheng Zheng, Jin Li, Jia Li, De-Pu Zhou, Xiao-Wei Li, Shu-Jie Wu and Jia-Feng Lin

    BMC Cardiovascular Disorders 2017 17:140

    Published on: 30 May 2017

  8. Research article

    Factors associated with length of stay following trans-catheter aortic valve replacement - a multicenter study

    Most patients undergoing Transcatheter aortic valve implantation (TAVR) are elderly with significant co-morbidities and there is limited information available regarding factors that influence length of stay (L...

    Yaron Arbel, Nevena Zivkovic, Dhruven Mehta, Sam Radhakrishnan, Stephen E. Fremes, Effat Rezaei, Asim N. Cheema, Sami Al-Nasser, Ariel Finkelstein and Harindra C. Wijeysundera

    BMC Cardiovascular Disorders 2017 17:137

    Published on: 26 May 2017

  9. Research article

    Cryoballoon vs. open irrigated radiofrequency ablation for paroxysmal atrial fibrillation: long-term FreezeAF outcomes

    Effective treatment of paroxysmal atrial fibrillation (AF) is essential for reducing the risk of stroke and heart failure. Cryoballoon (CB) ablation has been developed as an alternative to the use of radiofreq...

    Armin Luik, Kevin Kunzmann, Patrick Hörmann, Kerstin Schmidt, Andrea Radzewitz, Peter Bramlage, Thomas Schenk, Gerhard Schymik, Matthias Merkel, Meinhard Kieser and Claus Schmitt

    BMC Cardiovascular Disorders 2017 17:135

    Published on: 25 May 2017

  10. Research article

    Advanced glycation end products in children with type 1 diabetes and early reduced diastolic heart function

    Reduced diastolic function is an early sign of diabetes cardiomyopathy in adults and is associated with elevated levels of HbA1c and advanced glycation end products (AGEs).

    Leif Brunvand, Martin Heier, Cathrine Brunborg, Kristian F. Hanssen, Drude Fugelseth, Knut Haakon Stensaeth, Knut Dahl-Jørgensen and Hanna Dis Margeirsdottir

    BMC Cardiovascular Disorders 2017 17:133

    Published on: 25 May 2017

  11. Research article

    Impaired chronotropic response to physical activities in heart failure patients

    While exercise-based cardiac rehabilitation has a beneficial effect on heart failure hospitalization and mortality, it is limited by the presence of chronotropic incompetence (CI) in some patients. This study ...

    Hong Shen, Jianrong Zhao, Xiaohong Zhou, Jingbo Li, Qing Wan, Jing Huang, Hui Li, Liqun Wu, Shungang Yang and Ping Wang

    BMC Cardiovascular Disorders 2017 17:136

    Published on: 25 May 2017

  12. Case report

    The use of Macitentan in Fontan circulation: a case report

    The Fontan circulation, a result of a palliative procedure in patients with single systemic ventricles, is defined by chronically elevated pulmonary vascular resistance. When traditional heart failure therapie...

    Polyvios Demetriades, Amir Aziz, Robin Condliffe, Sarah E. Bowater and Paul F. Clift

    BMC Cardiovascular Disorders 2017 17:131

    Published on: 22 May 2017

  13. Research article

    Origins location of the outflow tract ventricular arrhythmias exhibiting qrS pattern or QS pattern with a notch on the descending limb in lead V1

    Ventricular outflow tract(VOT) ventricular arrhythmias(VAs) presenting qrS pattern or QS pattern with a notch on the descending limb in lead V1 were consistently thought of arising from the commissure between ...

    Cong Lin, Cheng Zheng, De-Pu Zhou, Xiao-Wei Li, Shu-Jie Wu and Jia-Feng Lin

    BMC Cardiovascular Disorders 2017 17:124

    Published on: 15 May 2017

  14. Research article

    Living with hypertrophic cardiomyopathy and an implantable defibrillator

    ICDs efficiently terminate life-threatening arrhythmias, but complications occur during long-term follow-up. Patients’ own perspective is largely unknown. The aim of the study was to describe experiences of hy...

    Peter Magnusson, Jessica Jonsson, Stellan Mörner and Lennart Fredriksson

    BMC Cardiovascular Disorders 2017 17:121

    Published on: 10 May 2017

  15. Case report

    Dramatic and early response to low-dose steroid in the treatment of acute eosinophilic myocarditis: a case report

    Eosinophilic myocarditis encompasses a variety of etiologies and the prognosis varies. For patients with a hypersensitive response to medications, high-dose corticosteroids and discontinuation of culprit medic...

    Yu-Wei Chen, Yu-Cheng Chang, Chieh-Shou Su, Wei-Chun Chang, Wen-Lieng Lee and Chih-Hung Lai

    BMC Cardiovascular Disorders 2017 17:115

    Published on: 8 May 2017

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